Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867413 | 0.85 | TRPV3 (0.46) | TRPV3KAT8ALDH1A1LMNAHPGD | |
| SCHEMBL9866569 | 0.82 | AR (0.51) | KAT8HPGDARKMT2ANPC1 | |
| SCHEMBL9866578 | 0.81 | TRPV3 (0.44) | TRPV3KAT8ALDH1A1LMNAHPGD | |
| SCHEMBL9866804 | 0.81 | POLB (0.47) | TRPV3KAT8ALDH1A1LMNAHPGD | |
| SCHEMBL9866908 | 0.79 | ALDH1A1 (0.39) | HSP90AA1HSP90AB1PDK1PDK2PDK3 | |
| SCHEMBL9866681 | 0.79 | KAT8 (0.47) | TRPV3KAT8ALDH1A1LMNAADAMTS4 | |
| SCHEMBL9865599 | 0.78 | KAT8 (0.41) | TRPV3KAT8PDK1PDK2PDK3 | |
| SCHEMBL9867527 | 0.77 | TRPV3 (0.44) | TRPV3KAT8ALDH1A1LMNAHPGD | |
| SCHEMBL9865486 | 0.76 | KMT2A (0.43) | TRPV3KAT8ALDH1A1HTTAR | |
| SCHEMBL9734839 | 0.76 | CA1 (0.50) | TRPV3KAT8ALDH1A1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| CN-1042144-A | Pesticidal compound | ICI PLC (GB) | 1990-05-16 | — | — | CN | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |