Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865969 | 0.82 | TRPV3 (0.45) | ARNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9867413 | 0.81 | TRPV3 (0.46) | ARNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9866681 | 0.80 | KAT8 (0.47) | MEN1KMT2AKAT8 | |
| SCHEMBL9865486 | 0.80 | KMT2A (0.43) | ARSMN1; SMN2MEN1KMT2AKAT8 | |
| SCHEMBL9734839 | 0.80 | CA1 (0.50) | MEN1KMT2AKAT8 | |
| SCHEMBL9866804 | 0.78 | POLB (0.47) | NPC1HPGDRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9866578 | 0.78 | TRPV3 (0.44) | ARHPGDSMN1; SMN2KAT8POLB | |
| SCHEMBL9867665 | 0.77 | KEAP1 (0.43) | PGRMEN1KMT2APOLB | |
| SCHEMBL9865599 | 0.77 | KAT8 (0.41) | ARNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL2524154 | 0.76 | L3MBTL1 (0.52) | RAB9ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |