Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 5/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865825 | 0.79 | NFE2L2 (0.33) | CA12CA1CA2CA9 | |
| SCHEMBL9865969 | 0.78 | TRPV3 (0.45) | KAT8ARTRPV3CA12CA2 | |
| SCHEMBL9866569 | 0.77 | AR (0.51) | KAT8ARNPC1HPGDRAB9A | |
| SCHEMBL9866804 | 0.77 | POLB (0.47) | KAT8TRPV3LMNANPC1HPGD | |
| SCHEMBL9867413 | 0.75 | TRPV3 (0.46) | KAT8ARTRPV3ADAMTS4MMP13 | |
| SCHEMBL9865486 | 0.74 | KMT2A (0.43) | KAT8ARTRPV3GRM5SMN1; SMN2 | |
| SCHEMBL9866681 | 0.74 | KAT8 (0.47) | KAT8TRPV3GRM5ADAMTS4LMNA | |
| SCHEMBL9734839 | 0.74 | CA1 (0.50) | KAT8TRPV3GRM5CA12CA1 | |
| SCHEMBL9866578 | 0.72 | TRPV3 (0.44) | KAT8ARTRPV3ADAMTS4MMP13 | |
| SCHEMBL2524154 | 0.71 | L3MBTL1 (0.52) | TRPV3GRM5NUDT1LMNAHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |