Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | IDH2 | P48735 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866569 | 0.80 | AR (0.51) | KMT2AMEN1KAT8SMN1; SMN2AR | |
| SCHEMBL9867413 | 0.78 | TRPV3 (0.46) | KAT8TRPV3HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL9866681 | 0.77 | KAT8 (0.47) | KMT2AMEN1KAT8TRPV3GRM5 | |
| SCHEMBL9734839 | 0.76 | CA1 (0.50) | KMT2AMEN1KAT8TRPV3GRM5 | |
| SCHEMBL9867278 | 0.76 | ALDH1A1 (0.37) | KMT2AMEN1RECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL9865969 | 0.76 | TRPV3 (0.45) | KMT2AKAT8TRPV3HTTALDH1A1 | |
| SCHEMBL9867726 | 0.76 | ALDH1A1 (0.39) | KMT2AMEN1RECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL9866578 | 0.75 | TRPV3 (0.44) | CYP2C19KAT8TRPV3HTTALDH1A1 | |
| SCHEMBL9866804 | 0.75 | POLB (0.47) | KMT2AMEN1KAT8TRPV3HTT | |
| SCHEMBL9865599 | 0.74 | KAT8 (0.41) | KAT8TRPV3GRM5SMN1; SMN2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| CN-1042144-A | Pesticidal compound | ICI PLC (GB) | 1990-05-16 | — | — | CN | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |