Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 3/20 | 0.35 |
| ▸ | IDH2 | P48735 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.33 |
| ▸ | PRKCG | P05129 | 2/20 | 0.33 |
| ▸ | PRKCB | P05771 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | PRKCH | P24723 | 2/20 | 0.33 |
| ▸ | PRKCI | P41743 | 2/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27350633 | 0.81 | PNMT (0.33) | PNMTPKMPIK3CDPIK3CBPIK3CG | |
| SCHEMBL9867001 | 0.79 | IDH2 (0.36) | IDH2KAT6AL3MBTL1ALDH1A1 | |
| SCHEMBL9735053 | 0.79 | ALDH1A1 (0.38) | PKMKMT2AMEN1CYP3A4CYP2D6 | |
| SCHEMBL9867686 | 0.78 | NFE2L2 (0.33) | PNMTPKMKMT2APIK3CDPIK3CB | |
| SCHEMBL9867938 | 0.78 | POLB (0.51) | PKMKMT2AMEN1LMNAGLRA3 | |
| SCHEMBL9866452 | 0.74 | ALDH1A1 (0.43) | PKMKMT2ALMNAALDH1A1 | |
| SCHEMBL22163647 | 0.73 | PTGS1 (0.33) | — | |
| SCHEMBL9868435 | 0.72 | L3MBTL1 (0.38) | KMT2AMEN1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL9378913 | 0.71 | KIF18A (0.47) | KMT2AMEN1CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL9868009 | 0.71 | KEAP1 (0.48) | PKMKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |