Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | PARG | Q86W56 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR1F | P30939 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867278 | 0.86 | ALDH1A1 (0.37) | ALDH1A1LMNABRD4BRD2BRD3 | |
| SCHEMBL9866318 | 0.80 | ALDH1A1 (0.36) | ALDH1A1LMNAL3MBTL1SMN1; SMN2HCAR1 | |
| SCHEMBL9867057 | 0.77 | ALDH1A1 (0.35) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL9865486 | 0.76 | KMT2A (0.43) | ALDH1A1MEN1KMT2ARECQLSMN1; SMN2 | |
| SCHEMBL9867665 | 0.75 | KEAP1 (0.43) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9865417 | 0.75 | SMN1; SMN2 (0.37) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9867995 | 0.74 | KMT2A (0.45) | ALDH1A1LMNABRD4BRD2BRD3 | |
| SCHEMBL9865854 | 0.74 | HCAR1 (0.39) | LMNASMN1; SMN2HCAR1HTR1DHTR1B | |
| SCHEMBL9865677 | 0.73 | HCAR1 (0.36) | HCAR1HTR1DHTR1BHTR1F | |
| SCHEMBL9866908 | 0.73 | ALDH1A1 (0.39) | ALDH1A1LMNABRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| CN-1042144-A | Pesticidal compound | ICI PLC (GB) | 1990-05-16 | — | — | CN | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |