Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 8/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 8/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 8/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871252 | 0.86 | CACNA1F (0.47) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL9869833 | 0.84 | CACNA1F (0.42) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL9871923 | 0.82 | ALDH1A1 (0.54) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL9870085 | 0.81 | GUSB (0.44) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL9871999 | 0.80 | ALDH1A1 (0.47) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL9869835 | 0.77 | CACNA1F (0.68) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL9870764 | 0.76 | POLB (0.45) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL7485042 | 0.72 | ALDH1A1 (0.39) | ALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL7533651 | 0.71 | MAPT (0.44) | LMNAMAPT | |
| SCHEMBL2451449 | 0.71 | ABCC9 (0.53) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071849-A | Antiinflammatory, antianginal agent | EGIS GYOGYSZERGYAR (HU) | 1991-12-10 | — | — | US | disclosed |