Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871923 | 0.86 | ALDH1A1 (0.54) | ALDH1A1LMNAKDM4EHPGDGUSB | |
| SCHEMBL9870085 | 0.85 | GUSB (0.44) | ALDH1A1LMNAGUSBCA1CA2 | |
| SCHEMBL9475138 | 0.82 | ALDH1A1 (0.53) | ALDH1A1GAALMNAKDM4EHPGD | |
| SCHEMBL9869503 | 0.80 | CACNA1F (0.44) | ALDH1A1LMNACA1CA2MAPT | |
| SCHEMBL9871252 | 0.74 | CACNA1F (0.47) | ALDH1A1LMNAMAPTNPSR1KMT2A | |
| SCHEMBL9869835 | 0.73 | CACNA1F (0.68) | ALDH1A1LMNAGUSBKMT2ACACNA1D | |
| SCHEMBL27517088 | 0.71 | KDM4E (0.68) | ALDH1A1GAALMNAKDM4EHPGD | |
| SCHEMBL9870739 | 0.71 | ALDH1A1 (0.36) | ALDH1A1GAALMNAKDM4ECA1 | |
| SCHEMBL9871507 | 0.71 | L3MBTL1 (0.42) | ALDH1A1GAALMNAKDM4EHPGD | |
| SCHEMBL7347481 | 0.70 | GUSB (0.70) | ALDH1A1GAAKDM4EGUSBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071849-A | Antiinflammatory, antianginal agent | EGIS GYOGYSZERGYAR (HU) | 1991-12-10 | — | — | US | disclosed |