Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 5/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 5/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 5/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870308 | 0.86 | POLB (0.37) | POLBCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL9871923 | 0.77 | ALDH1A1 (0.54) | CACNA1FCACNA1DCACNA1SCACNA1CMAPT | |
| SCHEMBL9869503 | 0.76 | CACNA1F (0.44) | CACNA1FCACNA1DCACNA1SCACNA1CMAPT | |
| SCHEMBL6950055 | 0.74 | POLB (0.49) | POLBALOX15TP53MAPTALDH1A1 | |
| SCHEMBL9870929 | 0.73 | CACNA1F (0.40) | CACNA1FCACNA1DCACNA1SCACNA1CCA1 | |
| SCHEMBL9870085 | 0.72 | GUSB (0.44) | CACNA1FCACNA1DCACNA1SCACNA1CMAPT | |
| SCHEMBL9871999 | 0.70 | ALDH1A1 (0.47) | CACNA1FCACNA1DCACNA1SCACNA1CTP53 | |
| SCHEMBL9476788 | 0.70 | CACNA1F (0.67) | CACNA1FCACNA1DCACNA1SCACNA1CTP53 | |
| SCHEMBL9869835 | 0.70 | CACNA1F (0.68) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL9475571 | 0.68 | CACNA1F (0.65) | CACNA1FCACNA1DCACNA1SCACNA1CTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071849-A | Antiinflammatory, antianginal agent | EGIS GYOGYSZERGYAR (HU) | 1991-12-10 | — | — | US | disclosed |