Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870440 | 0.82 | L3MBTL1 (0.34) | LMNAHSD11B1KLK7ALDH1A1L3MBTL1 | |
| SCHEMBL4398729 | 0.81 | MGLL (0.36) | LMNAHSD11B1KLK7POLBMAPT | |
| SCHEMBL11233227 | 0.78 | SLC6A3 (0.39) | HSD11B1KIF11 | |
| SCHEMBL2083953 | 0.74 | CA12 (0.39) | LMNAALDH1A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL2747320 | 0.73 | HSD11B1 (0.46) | LMNAHSD11B1MEN1KMT2A | |
| SCHEMBL13067194 | 0.69 | PRKCG (0.38) | L3MBTL1TSHRSMN1; SMN2MAPT | |
| SCHEMBL1608747 | 0.69 | SLC6A3 (0.47) | LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2085855 | 0.68 | HSD11B1 (0.34) | LMNAHSD11B1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4612086 | 0.68 | MAPT (0.39) | LMNAALDH1A1L3MBTL1POLBTSHR | |
| SCHEMBL13067135 | 0.68 | HSD11B1 (0.34) | HSD11B1L3MBTL1TSHRSMN1; SMN2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077288-A | Adrenergic, serotonin and histamine antagonist | ADIR ET COMPAGNIE (FR) | 1991-12-31 | — | — | US | disclosed |