Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869830 | 0.82 | HTR6 (0.33) | L3MBTL1HSD11B1LMNAKLK7MAPT | |
| SCHEMBL4398729 | 0.78 | MGLL (0.36) | HSD11B1LMNAKLK7MAPTHPGD | |
| SCHEMBL2083953 | 0.71 | CA12 (0.39) | LMNAMAPTHPGDMEN1KMT2A | |
| SCHEMBL2747320 | 0.70 | HSD11B1 (0.46) | HSD11B1LMNAMEN1KMT2A | |
| SCHEMBL10011229 | 0.69 | ADRA2A (0.44) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8537470 | 0.66 | ALDH1A1 (0.40) | L3MBTL1LMNAMAPTHPGDMEN1 | |
| SCHEMBL31377741 | 0.66 | HSD11B1 (0.53) | HSD11B1MEN1KMT2A | |
| SCHEMBL13067194 | 0.66 | PRKCG (0.38) | L3MBTL1MAPT | |
| SCHEMBL11248214 | 0.65 | SLC6A3 (0.34) | LMNASLC6A4MEN1KMT2A | |
| SCHEMBL7557937 | 0.65 | EGFR (0.36) | LMNASLC6A4MEN1KMT2ACCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077288-A | Adrenergic, serotonin and histamine antagonist | ADIR ET COMPAGNIE (FR) | 1991-12-31 | — | — | US | disclosed |