SCHEMBL987761

SCHEMBL987761

COc1ccc(-c2cc(=O)c3c(OC)cc(OC)c(OC)c3o2)cc1OC

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.78
MAPT P10636 3/20 0.78
MEN1 O00255 3/20 0.78
KMT2A Q03164 3/20 0.78
CYP3A4 P08684 2/20 0.78
MAPK1 P28482 2/20 0.78
ABCB1 P08183 2/20 0.78
ABCG2 Q9UNQ0 2/20 0.78
KDM4E B2RXH2 2/20 0.78
HPGD P15428 1/20 0.78
HSD17B10 Q99714 1/20 0.78
USP2 O75604 1/20 0.71
LMNA P02545 1/20 0.71
ELANE P08246 1/20 0.71
TP53 P04637 1/20 0.70
MDM2 Q00987 1/20 0.70
CYP1A1 P04798 3/20 0.64
CYP1A2 P05177 3/20 0.64
CYP1B1 Q16678 3/20 0.64
OPRD1 P41143 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29419950 1.00 ALDH1A1 (0.78) ALDH1A1MAPTMEN1KMT2ACYP3A4
SCHEMBL30235468 1.00 ALDH1A1 (0.78) ALDH1A1MAPTMEN1KMT2ACYP3A4
SCHEMBL16894618 0.89 ALDH1A1 (0.71) ALDH1A1MAPTMEN1KMT2ACYP3A4
SCHEMBL6613762 0.88 ALDH1A1 (0.73) ALDH1A1MAPTMEN1KMT2ACYP3A4
SCHEMBL4057928 0.88 ACHE (0.76) ALDH1A1MAPTMEN1KMT2ACYP3A4
Nobiletin SCHEMBL30049859 0.88 ALDH1A1 (1.00) ALDH1A1MAPTMEN1KMT2ACYP3A4
Nobiletin SCHEMBL244029 0.88 ALDH1A1 (1.00) ALDH1A1MAPTMEN1KMT2ACYP3A4
Nobiletin SCHEMBL29374681 0.88 ALDH1A1 (1.00) ALDH1A1MAPTMEN1KMT2ACYP3A4
Nobiletin SCHEMBL22092292 0.88 ALDH1A1 (1.00) ALDH1A1MAPTMEN1KMT2ACYP3A4
Nobiletin SCHEMBL30049905 0.88 ALDH1A1 (1.00) ALDH1A1MAPTMEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119074820-A Polymethoxy flavone component enriched from pericarpium citri reticulatae, and enrichment method and application thereof 广东省中医院(广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院) 2024-12-06 CN claimed
CN-118121649-A Citrus extract, compound, and use thereof for inhibiting novel coronaviruses 丰苗生物科技股份有限公司 2024-06-04 CN claimed
US-20230119060-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING, AS ACTIVE INGREDIENT, COMPLEX OF BIGUANIDE-BASED COMPOUND AND FLAVONE, HYDROXYFLAVONE, FLAVANONE, FLAVONE DERIVATIVE, HYDROXYFLAVONE DERIVATIVE, OR FLAVANONE DERIVATIVE MEDIENCE CO., LTD. (KR) 2023-04-20 US claimed
US-9669003-B2 Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs JIN YONGRI (CN) 2017-06-06 US claimed
US-20150196529-A1 USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS JIN YONGRI (CN) 2015-07-16 US claimed
EP-2494874-B1 Control of flavor characteristics of fruit juice TROPICANA PROD INC (US) 2013-12-11 EP claimed
EP-2494874-A1 Control of flavor characteristics of fruit juice TROPICANA PRODUCTS, INC. (US) 2012-09-05 EP claimed
US-20110123653-A1 COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2011-05-26 US claimed
JP-2009506057-A 2009-02-12 JP claimed
EP-1928480-A2 METHODS FOR MANAGING ADIPOCYTE FAT ACCUMULATION Wellgen, Inc. (US) 2008-06-11 EP claimed
EP-1883300-A2 COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY Rutgers, The State University of New Jersey (US) 2008-02-06 EP claimed
US-20070088078-A1 Methods for managing adipocyte fat accumulation WELLGEN, INC. 2007-04-19 US claimed
US-7201928-B1 Extracts of orange peel for prevention and treatment of cancer RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2007-04-10 US claimed
WO-2007024982-A2 METHODS FOR MANAGING ADIPOCYTE FAT ACCUMULATION WELLGEN, INC. (US) 2007-03-01 WO claimed
US-20070042972-A1 Compositions and methods for optimizing exercise recovery RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2007-02-22 US claimed
WO-2006127996-A2 COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2006-11-30 WO claimed
US-6184246-B1 Inhibition of cytokine production by polymethoxylated flavones THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2001-02-06 US claimed
EP-0605261-B1 Use of a flavone derivative as taste modifier and a method of modifying taste SAN EI GEN FFI INC (JP) 1999-09-15 EP claimed
US-5580545-A ADDING FLAVONE DERIVATIVES TO FOODS, BEVERAGES OR TOILETRIES TO ENHANCE OR REDUCE FLAVORS SAN-EI GEN F.F.I., INC. (JP) 1996-12-03 US claimed
EP-0605261-A2 A taste modifier and a method of modifying taste SAN-EI GEN F.F.I., INC. (JP) 1994-07-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070042972-A1 Compositions and methods for optimizing exercise recovery GYS1, PYGM, PRDX5 ALDH1A1 3163/4885MAPT 4515/4885MEN1 4199/4885
US-20070088078-A1 Methods for managing adipocyte fat accumulation FABP4, PLIN5, PLIN3 ALDH1A1 1272/4885MAPT 3872/4885MEN1 4550/4885
US-20230119060-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING, AS ACTIVE INGREDIENT, COMPLEX OF BIGUANIDE-BASED COMPOUND AND FLAVONE, HYDROXYFLAVONE, FLAVANONE, FLAVONE DERIVATIVE, HYDROXYFLAVONE DERIVATIVE, OR FLAVANONE DERIVATIVE SLC5A2, SLC5A1, SLC5A6 ALDH1A1 2243/4885MAPT 3238/4885MEN1 617/4885
US-20110123653-A1 COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY GYS1, PYGM, PRDX5 ALDH1A1 3163/4885MAPT 4515/4885MEN1 4199/4885
US-20150196529-A1 USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS CYP2D6, GATAD2A, CYP3A43 ALDH1A1 668/4885MAPT 1508/4885MEN1 3778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.