Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.78 |
| ▸ | MEN1 | O00255 | 3/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.78 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.78 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | HPGD | P15428 | 1/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.78 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | ELANE | P08246 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.70 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.64 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29419950 | 1.00 | ALDH1A1 (0.78) | ALDH1A1MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL30235468 | 1.00 | ALDH1A1 (0.78) | ALDH1A1MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL16894618 | 0.89 | ALDH1A1 (0.71) | ALDH1A1MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL6613762 | 0.88 | ALDH1A1 (0.73) | ALDH1A1MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL4057928 | 0.88 | ACHE (0.76) | ALDH1A1MAPTMEN1KMT2ACYP3A4 | |
| Nobiletin SCHEMBL30049859 | 0.88 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2ACYP3A4 | |
| Nobiletin SCHEMBL244029 | 0.88 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2ACYP3A4 | |
| Nobiletin SCHEMBL29374681 | 0.88 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2ACYP3A4 | |
| Nobiletin SCHEMBL22092292 | 0.88 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2ACYP3A4 | |
| Nobiletin SCHEMBL30049905 | 0.88 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119074820-A | Polymethoxy flavone component enriched from pericarpium citri reticulatae, and enrichment method and application thereof | 广东省中医院(广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院) | 2024-12-06 | — | — | CN | claimed |
| CN-118121649-A | Citrus extract, compound, and use thereof for inhibiting novel coronaviruses | 丰苗生物科技股份有限公司 | 2024-06-04 | — | — | CN | claimed |
| US-20230119060-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING, AS ACTIVE INGREDIENT, COMPLEX OF BIGUANIDE-BASED COMPOUND AND FLAVONE, HYDROXYFLAVONE, FLAVANONE, FLAVONE DERIVATIVE, HYDROXYFLAVONE DERIVATIVE, OR FLAVANONE DERIVATIVE | MEDIENCE CO., LTD. (KR) | 2023-04-20 | — | — | US | claimed |
| US-9669003-B2 | Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs | JIN YONGRI (CN) | 2017-06-06 | — | — | US | claimed |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | JIN YONGRI (CN) | 2015-07-16 | — | — | US | claimed |
| EP-2494874-B1 | Control of flavor characteristics of fruit juice | TROPICANA PROD INC (US) | 2013-12-11 | — | — | EP | claimed |
| EP-2494874-A1 | Control of flavor characteristics of fruit juice | TROPICANA PRODUCTS, INC. (US) | 2012-09-05 | — | — | EP | claimed |
| US-20110123653-A1 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2011-05-26 | — | — | US | claimed |
| JP-2009506057-A | — | — | 2009-02-12 | — | — | JP | claimed |
| EP-1928480-A2 | METHODS FOR MANAGING ADIPOCYTE FAT ACCUMULATION | Wellgen, Inc. (US) | 2008-06-11 | — | — | EP | claimed |
| EP-1883300-A2 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | Rutgers, The State University of New Jersey (US) | 2008-02-06 | — | — | EP | claimed |
| US-20070088078-A1 | Methods for managing adipocyte fat accumulation | WELLGEN, INC. | 2007-04-19 | — | — | US | claimed |
| US-7201928-B1 | Extracts of orange peel for prevention and treatment of cancer | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2007-04-10 | — | — | US | claimed |
| WO-2007024982-A2 | METHODS FOR MANAGING ADIPOCYTE FAT ACCUMULATION | WELLGEN, INC. (US) | 2007-03-01 | — | — | WO | claimed |
| US-20070042972-A1 | Compositions and methods for optimizing exercise recovery | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2007-02-22 | — | — | US | claimed |
| WO-2006127996-A2 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2006-11-30 | — | — | WO | claimed |
| US-6184246-B1 | Inhibition of cytokine production by polymethoxylated flavones | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2001-02-06 | — | — | US | claimed |
| EP-0605261-B1 | Use of a flavone derivative as taste modifier and a method of modifying taste | SAN EI GEN FFI INC (JP) | 1999-09-15 | — | — | EP | claimed |
| US-5580545-A | ADDING FLAVONE DERIVATIVES TO FOODS, BEVERAGES OR TOILETRIES TO ENHANCE OR REDUCE FLAVORS | SAN-EI GEN F.F.I., INC. (JP) | 1996-12-03 | — | — | US | claimed |
| EP-0605261-A2 | A taste modifier and a method of modifying taste | SAN-EI GEN F.F.I., INC. (JP) | 1994-07-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070042972-A1 | Compositions and methods for optimizing exercise recovery | GYS1, PYGM, PRDX5 | ALDH1A1 3163/4885MAPT 4515/4885MEN1 4199/4885 |
| US-20070088078-A1 | Methods for managing adipocyte fat accumulation | FABP4, PLIN5, PLIN3 | ALDH1A1 1272/4885MAPT 3872/4885MEN1 4550/4885 |
| US-20230119060-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING, AS ACTIVE INGREDIENT, COMPLEX OF BIGUANIDE-BASED COMPOUND AND FLAVONE, HYDROXYFLAVONE, FLAVANONE, FLAVONE DERIVATIVE, HYDROXYFLAVONE DERIVATIVE, OR FLAVANONE DERIVATIVE | SLC5A2, SLC5A1, SLC5A6 | ALDH1A1 2243/4885MAPT 3238/4885MEN1 617/4885 |
| US-20110123653-A1 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | GYS1, PYGM, PRDX5 | ALDH1A1 3163/4885MAPT 4515/4885MEN1 4199/4885 |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | CYP2D6, GATAD2A, CYP3A43 | ALDH1A1 668/4885MAPT 1508/4885MEN1 3778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.