Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.55 |
| ▸ | DRD3 | P35462 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874358 | 0.89 | DRD2 (0.58) | DRD2DRD3LMNAPOLBGAA | |
| SCHEMBL9873640 | 0.85 | DRD2 (0.47) | DRD2DRD3LMNAPOLBGAA | |
| SCHEMBL9873718 | 0.84 | LMNA (0.43) | DRD2DRD3LMNAPOLBGAA | |
| SCHEMBL9872840 | 0.80 | LMNA (0.54) | DRD2DRD3LMNAPOLBGAA | |
| SCHEMBL9873593 | 0.79 | DRD2 (0.57) | DRD2DRD3LMNAPOLBGAA | |
| SCHEMBL9871472 | 0.75 | HTR1A (0.53) | DRD2DRD3 | |
| SCHEMBL7881721 | 0.73 | DRD2 (0.45) | DRD2DRD3LMNAPOLBGAA | |
| SCHEMBL9874903 | 0.72 | SIGMAR1 (0.43) | DRD2DRD3LMNAPOLBGAA | |
| SCHEMBL10075564 | 0.71 | DRD2 (1.00) | DRD2DRD3MAPT | |
| SCHEMBL9872533 | 0.71 | DRD2 (0.49) | DRD2DRD3LMNAPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988699-A | Treatment of psychological disorders such as schizophrenia, as antipsychotic agents and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |