Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373448 | 0.85 | RORC (0.66) | NPC1ALDH1A1MAPTRXFP1RORC | |
| SCHEMBL9874486 | 0.84 | MAPT (0.56) | NPC1ALDH1A1MAPTRXFP1PLK1 | |
| SCHEMBL9875019 | 0.84 | MEN1 (0.56) | NPC1ALDH1A1MAPTRXFP1PLK1 | |
| SCHEMBL9872839 | 0.83 | RAB9A (0.59) | NPC1MAPTRXFP1KDRPLK1 | |
| SCHEMBL9874407 | 0.81 | F10 (0.59) | NPC1ALDH1A1MAPTRXFP1PLK1 | |
| SCHEMBL22734230 | 0.77 | ALDH1A1 (0.65) | NPC1ALDH1A1MAPTRXFP1RORC | |
| SCHEMBL9872671 | 0.77 | SMN1; SMN2 (0.49) | MAPTPLK1PLK3GAALMNA | |
| SCHEMBL9875470 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPTKDRPLK1PLK3 | |
| SCHEMBL7372951 | 0.76 | KMT2A (0.69) | NPC1ALDH1A1MAPTRXFP1KDR | |
| SCHEMBL26416850 | 0.76 | ALDH1A1 (0.67) | NPC1ALDH1A1MAPTRXFP1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |