Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | MDM4 | O15151 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874486 | 0.88 | MAPT (0.56) | RAB9AGAAPLK1PLK3KMT2A | |
| SCHEMBL9875019 | 0.88 | MEN1 (0.56) | RAB9ACYP1A2CYP2D6CYP2C19PLK1 | |
| SCHEMBL9874407 | 0.85 | F10 (0.59) | RAB9AGAAPLK1PLK3TP53 | |
| SCHEMBL9873952 | 0.83 | NPC1 (0.54) | RAB9ACYP2D6GAAPLK1PLK3 | |
| SCHEMBL9872671 | 0.81 | SMN1; SMN2 (0.49) | RAB9ACYP1A2CYP2C19GAAPLK1 | |
| SCHEMBL9875470 | 0.80 | ALDH1A1 (0.48) | RAB9ACYP1A2CYP2C19GAAPLK1 | |
| SCHEMBL9872356 | 0.76 | SMN1; SMN2 (0.52) | GAAKMT2ARXFP1MEN1SMN1; SMN2 | |
| SCHEMBL9874730 | 0.76 | CETP (0.46) | CYP1A2CYP2C19GAAPLK1PLK3 | |
| SCHEMBL21652249 | 0.75 | RAB9A (0.62) | RAB9ACYP1A2CYP2D6CYP2C19GAA | |
| SCHEMBL20822075 | 0.74 | TYK2 (0.57) | PLK1PLK3KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |