Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875019 | 0.87 | MEN1 (0.56) | SMN1; SMN2CYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL9875470 | 0.84 | ALDH1A1 (0.48) | CYP1A2GAAMEN1KMT2AMAPT | |
| SCHEMBL9874706 | 0.82 | NTRK1 (0.49) | SMN1; SMN2LMNARAB9AHDAC1TP53 | |
| SCHEMBL9874486 | 0.82 | MAPT (0.56) | SMN1; SMN2TDP1GAAMEN1KMT2A | |
| SCHEMBL9872839 | 0.81 | RAB9A (0.59) | SMN1; SMN2CYP1A2GAAMEN1KMT2A | |
| SCHEMBL9874407 | 0.79 | F10 (0.59) | SMN1; SMN2GAAKMT2AMAPTLMNA | |
| SCHEMBL9872356 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2TDP1GAAMEN1KMT2A | |
| SCHEMBL15233687 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2POLBTDP1CYP1A2CYP3A4 | |
| SCHEMBL9873952 | 0.77 | NPC1 (0.54) | SMN1; SMN2POLBGAAMEN1KMT2A | |
| SCHEMBL9874730 | 0.75 | CETP (0.46) | SMN1; SMN2POLBCYP1A2CYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |