Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875019 | 0.86 | MEN1 (0.56) | NPC1RAB9AKMT2ARXFP1MAPT | |
| SCHEMBL9874486 | 0.86 | MAPT (0.56) | NPC1RAB9AKMT2ARXFP1MAPT | |
| SCHEMBL9872839 | 0.85 | RAB9A (0.59) | NPC1RAB9AKMT2ARXFP1MAPT | |
| SCHEMBL9873952 | 0.81 | NPC1 (0.54) | NPC1RAB9AKMT2ARXFP1MAPT | |
| SCHEMBL9872671 | 0.79 | SMN1; SMN2 (0.49) | RAB9AKMT2AHDAC1HDAC6MAPT | |
| SCHEMBL9875470 | 0.78 | ALDH1A1 (0.48) | RAB9AKMT2AHDAC1HDAC6MAPT | |
| SCHEMBL9872356 | 0.74 | SMN1; SMN2 (0.52) | KMT2ARXFP1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL7245758 | 0.74 | F10 (0.59) | F10NPC1RAB9AKMT2AHDAC1 | |
| SCHEMBL9874730 | 0.74 | CETP (0.46) | KMT2AKDM4ESMN1; SMN2LMNAPLK1 | |
| SCHEMBL314038 | 0.74 | F10 (0.77) | F10NPC1RAB9AKMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |