Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874486 | 0.89 | MAPT (0.56) | MEN1KMT2APLK1PLK3SMN1; SMN2 | |
| SCHEMBL9872839 | 0.88 | RAB9A (0.59) | MEN1KMT2APLK1PLK3CYP1A2 | |
| SCHEMBL9872671 | 0.87 | SMN1; SMN2 (0.49) | MEN1KMT2APLK1PLK3CYP1A2 | |
| SCHEMBL9874407 | 0.86 | F10 (0.59) | KMT2APLK1PLK3SMN1; SMN2ALDH1A1 | |
| SCHEMBL9873952 | 0.84 | NPC1 (0.54) | MEN1KMT2APLK1PLK3CYP2D6 | |
| SCHEMBL9875470 | 0.84 | ALDH1A1 (0.48) | MEN1KMT2APLK1PLK3CYP1A2 | |
| SCHEMBL9874706 | 0.82 | NTRK1 (0.49) | SMN1; SMN2RXFP1LMNANPC1RAB9A | |
| SCHEMBL9872356 | 0.80 | SMN1; SMN2 (0.52) | MEN1KMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9874730 | 0.77 | CETP (0.46) | MEN1KMT2APLK1PLK3CYP1A2 | |
| SCHEMBL21652294 | 0.76 | MEN1 (0.70) | MEN1KMT2ACYP1A2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |