Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BCL3 | P20749 | 1/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872356 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2RXFP1LMNA | |
| SCHEMBL9872671 | 0.82 | SMN1; SMN2 (0.49) | HDAC1SMN1; SMN2RAB9ATP53LMNA | |
| SCHEMBL9875019 | 0.82 | MEN1 (0.56) | SMN1; SMN2NPC1RXFP1RAB9ALMNA | |
| SCHEMBL9875470 | 0.77 | ALDH1A1 (0.48) | HDAC1RAB9ALMNA | |
| SCHEMBL9874486 | 0.74 | MAPT (0.56) | SMN1; SMN2NPC1RXFP1RAB9ALMNA | |
| SCHEMBL17664250 | 0.74 | KDM4E (0.52) | NTRK1HDAC1SMN1; SMN2NPC1RXFP1 | |
| SCHEMBL9872839 | 0.73 | RAB9A (0.59) | SMN1; SMN2NPC1RXFP1RAB9ATP53 | |
| SCHEMBL9874730 | 0.73 | CETP (0.46) | SMN1; SMN2LMNA | |
| SCHEMBL21870353 | 0.73 | HTT (0.56) | NTRK1HDAC1NPC1RAB9ABCL3 | |
| SCHEMBL3846350 | 0.72 | SMN1; SMN2 (0.64) | NTRK1SMN1; SMN2NPC1RXFP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |