Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874706 | 0.86 | NTRK1 (0.49) | SMN1; SMN2RXFP1LMNA | |
| SCHEMBL9875019 | 0.80 | MEN1 (0.56) | SMN1; SMN2RXFP1L3MBTL1MEN1KMT2A | |
| SCHEMBL9872671 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL9875470 | 0.78 | ALDH1A1 (0.48) | MEN1KMT2ALMNAGAAALDH1A1 | |
| SCHEMBL9874486 | 0.77 | MAPT (0.56) | SMN1; SMN2TRPV1RXFP1L3MBTL1TDP1 | |
| SCHEMBL30313345 | 0.76 | CES2 (0.48) | TDP1MEN1KMT2A | |
| SCHEMBL716995 | 0.76 | CES2 (0.48) | TDP1MEN1KMT2A | |
| SCHEMBL9872839 | 0.76 | RAB9A (0.59) | SMN1; SMN2TRPV1RXFP1L3MBTL1MEN1 | |
| SCHEMBL15233689 | 0.76 | CES2 (0.47) | SMN1; SMN2RXFP1L3MBTL1TDP1MEN1 | |
| SCHEMBL9874730 | 0.76 | CETP (0.46) | SMN1; SMN2L3MBTL1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017576-A | Antianxiolytic, hypnotic, anticonvulsant, antiepileptic | RHONE-POULENC SANTE (FR) | 1991-05-21 | — | — | US | disclosed |