Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.51 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CHRND | Q07001 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879560 | 0.81 | SIGMAR1 (0.43) | MAPTTHRBSIGMAR1MEN1KMT2A | |
| SCHEMBL18965040 | 0.79 | KDM4E (0.48) | MAPTTHRBSIGMAR1CCR1CNR1 | |
| SCHEMBL13231742 | 0.79 | SIGMAR1 (0.47) | MAPTTHRBSIGMAR1CCR1CNR1 | |
| SCHEMBL5954545 | 0.76 | SLC6A3 (0.66) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL5953978 | 0.75 | SLC6A2 (0.68) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL4231835 | 0.74 | KCNH2 (0.52) | MAPTTHRBSIGMAR1CCR1MEN1 | |
| SCHEMBL13231740 | 0.74 | SIGMAR1 (0.43) | MAPTTHRBSIGMAR1CCR1CNR1 | |
| SCHEMBL5954170 | 0.74 | MC4R (0.57) | MAPTMEN1KMT2ACHRNA1CHRNG | |
| SCHEMBL5954184 | 0.73 | PHGDH (0.55) | MAPTTHRBKMT2ACHRNA1CHRNG | |
| SCHEMBL7094264 | 0.73 | OPRD1 (0.52) | MAPTSIGMAR1CHRNA1CHRNGCHRNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008200-A1 | NOVEL TETRAHYDROPYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS AS ACTIVE AGENTS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1991-06-13 | — | — | WO | claimed |