Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879617 | 0.81 | MAPT (0.53) | SIGMAR1MEN1KMT2ASLC6A3SLC6A2 | |
| SCHEMBL9879561 | 0.75 | SIGMAR1 (0.70) | SIGMAR1MEN1KMT2AHTR1APPARG | |
| SCHEMBL10240614 | 0.71 | LMNA (0.50) | SIGMAR1HRH3KCNH2MEN1KMT2A | |
| SCHEMBL25270979 | 0.71 | MEN1 (0.45) | SIGMAR1HRH3KCNH2MEN1KMT2A | |
| SCHEMBL895863 | 0.70 | SLC6A3 (0.65) | SIGMAR1CHRM2ADRA2BDRD3HRH3 | |
| SCHEMBL17644179 | 0.70 | SLC6A3 (0.65) | SIGMAR1CHRM2ADRA2BDRD3HRH3 | |
| SCHEMBL4231835 | 0.70 | KCNH2 (0.52) | SIGMAR1HRH3KCNH2MEN1KMT2A | |
| SCHEMBL14348177 | 0.69 | ALDH1A1 (0.51) | MEN1KMT2AMAPTLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL17645636 | 0.69 | SLC6A3 (0.63) | SIGMAR1CHRM2ADRA2BDRD3HRH3 | |
| SCHEMBL9879635 | 0.68 | MEN1 (0.52) | HRH3KCNH2MEN1KMT2ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008200-A1 | NOVEL TETRAHYDROPYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS AS ACTIVE AGENTS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1991-06-13 | — | — | WO | claimed |