Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.66 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.66 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.66 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.66 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.66 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.66 |
| ▸ | CHRNG | P07510 | 4/20 | 0.66 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.66 |
| ▸ | CHRND | Q07001 | 4/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5953978 | 0.98 | SLC6A2 (0.68) | SLC6A3SLC6A2CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL5954170 | 0.87 | MC4R (0.57) | SLC6A3SLC6A2CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL5954184 | 0.85 | PHGDH (0.55) | SLC6A3SLC6A2CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL7094264 | 0.85 | OPRD1 (0.52) | SLC6A3SLC6A2CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL895863 | 0.84 | SLC6A3 (0.65) | SLC6A3SLC6A2CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL7946750 | 0.84 | SLC6A3 (0.60) | SLC6A3SLC6A2CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL17644179 | 0.84 | SLC6A3 (0.65) | SLC6A3SLC6A2CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL9597385 | 0.83 | SLC6A3 (0.61) | SLC6A3SLC6A2CHRNB4CHRNA3CHRNB2 | |
| Hydrochloric Acid SCHEMBL17645636 | 0.83 | SLC6A3 (0.63) | SLC6A3SLC6A2CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL6811754 | 0.83 | ALDH1A1 (0.61) | SLC6A3SLC6A2CHRNB4CHRNA3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230204512-A1 | DETECTION PLATFORM AND METHOD FOR DETECTING ABUSED DRUGS | NATIONAL TAIWAN UNIVERSITY (TW) | 2023-06-29 | — | — | US | disclosed |
| US-20060058374-A1 | Urotensin II receptor agents | ACADIA PHARMACEUTICALS INC. | 2006-03-16 | — | — | US | disclosed |
| US-20040077529-A1 | Urotensin II receptor agents | ACADIA PHARMACEUTICALS, INC. | 2004-04-22 | — | — | US | disclosed |
| WO-2003104216-A1 | UROTENSIN II RECEPTOR MODULATORS | ACADIA PHARMACEUTICALS INC. (US) | 2003-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077529-A1 | Urotensin II receptor agents | UTS2R, PLAUR, GPR17 | SLC6A3 1816/4885SLC6A2 1143/4885CHRNB4 2731/4885 |
| US-20060058374-A1 | Urotensin II receptor agents | UTS2R, PLAUR, SCTR | SLC6A3 1491/4885SLC6A2 1016/4885CHRNB4 2724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.