Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874916 | 0.79 | SMN1; SMN2 (0.42) | LMNAMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL9874920 | 0.75 | TDP1 (0.47) | LMNAMAPTALDH1A1RAB9AHPGD | |
| SCHEMBL9874472 | 0.71 | SMN1; SMN2 (0.37) | MAPTSMN1; SMN2ALDH1A1RAB9AHPGD | |
| SCHEMBL9873674 | 0.69 | KMT2A (0.42) | LMNAMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9381137 | 0.69 | GABRP (0.39) | LMNASMN1; SMN2ALDH1A1RAB9AHPGD | |
| SCHEMBL9872674 | 0.66 | ALDH1A1 (0.45) | LMNAMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL11819922 | 0.65 | MAPT (0.68) | MAPTSMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL11801105 | 0.65 | MAPK1 (0.56) | MAPTSMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL11384657 | 0.65 | GABRP (0.64) | LMNAMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL28443847 | 0.65 | GRM4 (0.62) | MAPTSMN1; SMN2RAB9ATHRBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | claimed |