SCHEMBL988446

SCHEMBL988446

Cc1cc(C(=O)C2C(=O)CCCC2=O)c(C)c2c1S(O)(O)CCC2Oc1ncccn1

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SPR P35270 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL988443 0.90 SPR (0.40) SPR
SCHEMBL1963019 0.76 SPR (0.38) SPR
SCHEMBL9004024 0.74 SPR (0.41) SPR
SCHEMBL7853482 0.73
SCHEMBL9004078 0.72 SPR (0.40) SPR
SCHEMBL6772639 0.72 SPR (0.40) SPR
SCHEMBL6901695 0.72
SCHEMBL7833058 0.70 ALDH1A1 (0.41) SPR
SCHEMBL7974532 0.67 SPR (0.36) SPR
SCHEMBL6768806 0.65 SPR (0.48) SPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100261680-A1 HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULPHONYLAMINO(THIO)CARBONYL-TRIAZOLIN(ETHI)ONES BAYER CROPSCIENCE AG (DE) 2010-10-14 US claimed
US-20050192182-A1 Herbicidal mixtures based on substituted aryl ketones BAYER CROPSCIENCE AG (DE) 2005-09-01 US claimed
US-20050090396-A1 Herbicides based on substituted carboxylic acid anilides BAYER CROPSCIENCE AG (DE) 2005-04-28 US claimed
US-20050085388-A1 Selective herbicide comprising a tetrazolinone derivative BAYER CROPSCIENCE AG (DE) 2005-04-21 US claimed
US-20050003963-A1 Herbicides containing substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)one BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-01-06 US claimed
EP-1423010-A2 SELECTIVE HERBICIDE COMPRISING A TETRAZOLINONE DERIVATIVE Bayer CropScience AG (DE) 2004-06-02 EP claimed
WO-2003020035-A2 SELECTIVE HERBICIDE COMPRISING A TETRAZOLINONE DERIVATIVE BAYER CROPSCIENCE AG (DE) 2003-03-13 WO claimed
US-11202447-B2 Herbicides based on substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(thi)ones and 4-HPPD-inhibitors BAYER INTELLECTUAL PROPERTY GMBH (DE) 2021-12-21 US disclosed
EP-2842426-B1 Herbicide based on a substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)one and a 4-HPPD inhibitor BAYER CROPSCIENCE AG (DE) 2017-09-27 EP disclosed
US-9055748-B2 Herbicides containing substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)one BAYER CROPSCIENCE AG (DE) 2015-06-16 US disclosed
EP-2842426-A1 New herbicide based on substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)ones and 4-HPPD inhibitors Bayer CropScience AG (DE) 2015-03-04 EP disclosed
EP-1725100-B1 HERBICIDES BASED ON SUBSTITUTED THIEN-3-YL-SULPHONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES AND 4-HPPD-INHIBITORS BAYER CROPSCIENCE AG (DE) 2014-11-05 EP disclosed
US-8648014-B2 Herbicides containing substituted thien-3-yl-sulphonylaminio(thio)carbonyl-triazolin(ethi)ones BAYER CROPSCIENCE AG (DE) 2014-02-11 US disclosed
US-20050192182-A1 Herbicidal mixtures based on substituted aryl ketones BAYER CROPSCIENCE AG (DE) 2005-09-01 US disclosed
US-20050090396-A1 Herbicides based on substituted carboxylic acid anilides BAYER CROPSCIENCE AG (DE) 2005-04-28 US disclosed
US-20050090397-A1 Herbicides made from substituted aryl ketones BAYER CROPSCIENCE AG (GB) 2005-04-28 US disclosed
US-20050085388-A1 Selective herbicide comprising a tetrazolinone derivative BAYER CROPSCIENCE AG (DE) 2005-04-21 US disclosed
US-20050003963-A1 Herbicides containing substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)one BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-01-06 US disclosed
EP-1423005-A1 HERBICIDAL MIXTURES BASED ON SUBSTITUTED ARYL KETONES Bayer CropScience AG (DE) 2004-06-02 EP disclosed
WO-2003020033-A1 HERBICIDAL MIXTURES BASED ON SUBSTITUTED ARYL KETONES BAYER CROPSCIENCE AG (DE) 2003-03-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050192182-A1 Herbicidal mixtures based on substituted aryl ketones DDT, CBR3, CYP1B1 SPR 3161/4885
US-20050090396-A1 Herbicides based on substituted carboxylic acid anilides AADAC, NOTUM, NAAA SPR 1157/4885
US-20050090397-A1 Herbicides made from substituted aryl ketones DDT, CBR3, CBR1 SPR 3677/4885
US-20050003963-A1 Herbicides containing substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)one DDT, TARS2, CBR3 SPR 1096/4885
US-11202447-B2 Herbicides based on substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(thi)ones and 4-HPPD-inhibitors HPD, DDT, TH SPR 92/4885
US-20050085388-A1 Selective herbicide comprising a tetrazolinone derivative DDT, DYRK4, DYRK3 SPR 2222/4885
US-20100261680-A1 HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULPHONYLAMINO(THIO)CARBONYL-TRIAZOLIN(ETHI)ONES DDT, TARS2, TST SPR 1591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.