SCHEMBL9890928

SCHEMBL9890928

COc1ccc(-c2c3ccccc3c(-c3cccc(-c4ccc5c(c4)c4ccccc4n5C)c3)c3ccccc23)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.64
KDM4E B2RXH2 5/20 0.64
ALDH1A1 P00352 5/20 0.64
HPGD P15428 5/20 0.64
KMT2A Q03164 2/20 0.64
HSD17B10 Q99714 2/20 0.64
MEN1 O00255 1/20 0.64
MAPT P10636 1/20 0.64
HTT P42858 1/20 0.64
ACHE P22303 3/20 0.48
BCHE P06276 2/20 0.48
TSPO P30536 2/20 0.47
USP2 O75604 1/20 0.46
ABL1 P00519 1/20 0.45
ABCB1 P08183 1/20 0.45
BCR P11274 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
ATM Q13315 2/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9890924 0.89 GPR3 (0.52) L3MBTL1KDM4EALDH1A1HPGDKMT2A
SCHEMBL15196326 0.84 GPR3 (0.53) L3MBTL1KDM4EALDH1A1HPGDKMT2A
SCHEMBL15196349 0.84 GPR3 (0.53) L3MBTL1KDM4EALDH1A1HPGDKMT2A
SCHEMBL17125563 0.84 GPR3 (0.61) L3MBTL1KDM4EALDH1A1HPGDKMT2A
SCHEMBL9890927 0.82 KIF11 (0.46) L3MBTL1KDM4EALDH1A1HPGDKMT2A
SCHEMBL12721945 0.82 GPR3 (0.64) L3MBTL1KDM4EALDH1A1HPGDKMT2A
SCHEMBL6723905 0.81 GPR3 (0.57) L3MBTL1KDM4EALDH1A1HPGDKMT2A
SCHEMBL17722992 0.81 L3MBTL1 (0.61) L3MBTL1KDM4EALDH1A1HPGDKMT2A
SCHEMBL9890930 0.80 MAPT (0.44) L3MBTL1KDM4EALDH1A1HPGDKMT2A
SCHEMBL9890919 0.80 KDM4E (0.47) L3MBTL1KDM4EALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8502201-B2 Light-emitting element TORAY INDUSTRIES, INC. (JP) 2013-08-06 US disclosed
US-8502201-B2 Light-emitting element TORAY INDUSTRIES, INC. (JP) 2013-08-06 US disclosed
US-20120138907-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2012-06-07 US disclosed
US-20120138907-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2012-06-07 US disclosed
US-8084146-B2 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2011-12-27 US disclosed
US-8084146-B2 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2011-12-27 US disclosed
US-20110121268-A1 LIGHT-EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2011-05-26 US disclosed
US-20110121268-A1 LIGHT-EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2011-05-26 US disclosed
US-7901794-B2 Material for light-emitting element and light emitting element TORAY INDUSTRIES, INC. (JP) 2011-03-08 US disclosed
US-7901794-B2 Material for light-emitting element and light emitting element TORAY INDUSTRIES, INC. (JP) 2011-03-08 US disclosed
US-20090066245-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2009-03-12 US disclosed
US-20090066245-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2009-03-12 US disclosed
US-20070247063-A1 Light-Emitting Device Material and Light-Emitting Device TORAY INDUSTRIES INC. (JP) 2007-10-25 US disclosed
US-20070247063-A1 Light-Emitting Device Material and Light-Emitting Device TORAY INDUSTRIES INC. (JP) 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120138907-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE CRY1, MMS19, CRY2 L3MBTL1 167/4885KDM4E 3391/4885ALDH1A1 507/4885
US-20070247063-A1 Light-Emitting Device Material and Light-Emitting Device CRY1, CRY2, ATXN10 L3MBTL1 530/4885KDM4E 3893/4885ALDH1A1 426/4885
US-20090066245-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT PYM1, CRY1, S100A10 L3MBTL1 195/4885KDM4E 1639/4885ALDH1A1 2046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.