SCHEMBL9891445

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9891452	0.89	ALDH1A1 (0.48)	HDAC8HDAC1HDAC2HDAC3ALDH1A1
	SCHEMBL9891440	0.85	HDAC8 (0.46)	HDAC8SMN1; SMN2PPARAALDH1A1GAA
	SCHEMBL9891447	0.85	MAPT (0.53)	PDK1PDK2PDK3PDK4HDAC8
	SCHEMBL9892810	0.83	POLB (0.54)	HDAC8HDAC1HDAC2HDAC3HDAC4
	SCHEMBL9891431	0.83	HDAC8 (0.44)	HDAC8ALDH1A1GAAMAPTHTT
	SCHEMBL9891435	0.82	KMT2A (0.47)	HPGDALDH1A1GAAMAPTKMT2A
	SCHEMBL9891433	0.82	HDAC8 (0.42)	HDAC8HDAC1HDAC2HDAC3HDAC6
	SCHEMBL15613892	0.82	FFAR1 (0.61)	HDAC8HDAC1HDAC2HDAC3HDAC4
	SCHEMBL5151596	0.80	POLB (0.44)	PDK1PDK2PDK3PDK4ALDH1A1
	SCHEMBL9891441	0.80	POLB (0.42)	HDAC8SMN1; SMN2NPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.