SCHEMBL9891452

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5151596	0.90	POLB (0.44)	ALDH1A1MAPTLMNATOP2ACA1
	SCHEMBL9891445	0.89	PDK1 (0.47)	ALDH1A1MAPTHDAC3HDAC1HDAC2
	SCHEMBL15219206	0.88	ALDH1A1 (0.46)	ALDH1A1MAPTLMNATOP2AHDAC3
	SCHEMBL9891455	0.87	ALDH1A1 (0.44)	ALDH1A1MAPTLMNATOP2AHDAC3
	SCHEMBL9891435	0.87	KMT2A (0.47)	ALDH1A1MAPTLMNACA1CA2
	SCHEMBL9891433	0.86	HDAC8 (0.42)	ALDH1A1MAPTHDAC3HDAC1HDAC2
	SCHEMBL9891458	0.84	ALDH1A1 (0.42)	ALDH1A1MAPTLMNATOP2AHDAC3
	SCHEMBL9891460	0.84	ALDH1A1 (0.42)	ALDH1A1MAPTLMNATOP2AHDAC3
	SCHEMBL9891441	0.84	POLB (0.42)	ALDH1A1MAPTLMNAHDAC8FPR3
	SCHEMBL9891447	0.84	MAPT (0.53)	ALDH1A1MAPTHDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.