SCHEMBL9891435

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9891452	0.87	ALDH1A1 (0.48)	ALDH1A1CA1CA2MAPTLMNA
	SCHEMBL9892803	0.84	CA1 (0.45)	ALDH1A1CA1CA2CA12CA9
	SCHEMBL9891445	0.82	PDK1 (0.47)	KMT2AALDH1A1HPGDMAPTGAA
	SCHEMBL15613898	0.81	ALDH1A1 (0.63)	KMT2AMEN1TSHRALDH1A1CA1
	SCHEMBL9891433	0.80	HDAC8 (0.42)	KMT2AMEN1ALDH1A1CA1CA2
	SCHEMBL5151596	0.78	POLB (0.44)	ALDH1A1CA1CA2CA12CA9
	SCHEMBL9891447	0.78	MAPT (0.53)	ALDH1A1MAPTGAA
	SCHEMBL9891440	0.78	HDAC8 (0.46)	ALDH1A1CA1CA2MAPTKDM4E
	SCHEMBL16369813	0.78	POLB (0.42)	CYP1A2CYP3A4CA1CA2MAPT
	SCHEMBL9891441	0.78	POLB (0.42)	CYP1A2CYP3A4ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.