Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL356681 | 0.90 | ALDH1A1 (0.80) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| SCHEMBL3970272 | 0.88 | ALDH1A1 (0.77) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| SCHEMBL3307167 | 0.81 | ALDH1A1 (0.67) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| SCHEMBL3302369 | 0.81 | ALDH1A1 (0.67) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| SCHEMBL147877 | 0.81 | ALDH1A1 (0.67) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| Hydronidone SCHEMBL143564 | 0.81 | ALDH1A1 (0.67) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| SCHEMBL3975362 | 0.81 | ALDH1A1 (0.67) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| Pirfenidone SCHEMBL1006039 | 0.80 | KDM4E (1.00) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| SCHEMBL3306599 | 0.80 | ALDH1A1 (0.66) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| Pirfenidone SCHEMBL4708 | 0.80 | KDM4E (1.00) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118619937-A | Benzotriazine double oxide and pharmaceutical composition thereof | 浙江瑞臻医药有限公司 | 2024-09-10 | — | — | CN | disclosed |
| US-8426407-B2 | Preparation of 1-(substituted aryl)-5-trifluoromethyl-2-(1H)pyridone compounds and salts thereof and their applications | CENTRAL SOUTH UNIVERSITY (CN) | 2013-04-23 | — | — | US | disclosed |
| US-20120142688-A1 | PREPARATION OF 1-(SUBSTITUTED ARYL)-5-TRIFLUOROMETHYL-2-(1H)PYRIDONE COMPOUNDS AND SALTS THEREOF AND THEIR APPLICATIONS | CENTRAL SOUTH UNIVERSITY (CN) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142688-A1 | PREPARATION OF 1-(SUBSTITUTED ARYL)-5-TRIFLUOROMETHYL-2-(1H)PYRIDONE COMPOUNDS AND SALTS THEREOF AND THEIR APPLICATIONS | CFTR, COL1A1, FN1 | ALDH1A1 142/4885KDM4E 2004/4885HSD17B10 1439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.