Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902357 | 0.79 | P2RX7 (0.44) | ALDH1A1KDM4EGAAHTT | |
| SCHEMBL9902361 | 0.79 | P2RX7 (0.44) | ALDH1A1KDM4EGAAHTT | |
| SCHEMBL16994510 | 0.79 | P2RX7 (0.44) | ALDH1A1KDM4EGAAHTT | |
| SCHEMBL9901676 | 0.73 | TSHR (0.40) | ALDH1A1KDM4EHPGDHTT | |
| SCHEMBL16994511 | 0.73 | P2RX7 (0.41) | ALDH1A1KDM4EGAAHTT | |
| SCHEMBL15510403 | 0.72 | MAPT (0.74) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL14031230 | 0.70 | MAPT (0.61) | ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL9901681 | 0.70 | KMT2A (0.39) | ALDH1A1KDM4ENPSR1HPGDMITF | |
| SCHEMBL23666092 | 0.69 | ALDH1A1 (0.64) | ALDH1A1CA1CA2CA9 | |
| SCHEMBL9903243 | 0.69 | KDM4E (0.58) | ALDH1A1CA1CA2CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170107198-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | TISBURY PHARMACEUTICALS, INC | 2017-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170107198-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | NOX4, NOX1, NOS1 | ALDH1A1 1794/4885CA1 4186/4885CA2 844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.