Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902699 | 0.89 | HTR3A (0.48) | HTR6ALKHTR7HTR2BDRD2 | |
| SCHEMBL9903593 | 0.88 | GHSR (0.43) | HTR6ALKLMNAHSP90AA1MAPT | |
| SCHEMBL9903634 | 0.87 | HTR6 (0.50) | HTR6HTR7HTR1AHTR2BCHRNB2 | |
| SCHEMBL4690981 | 0.83 | HTR6 (0.61) | HTR6HTR7HTR1AHTR2BCHRNB2 | |
| SCHEMBL9903601 | 0.82 | HTR6 (0.47) | HTR6HTR7HTR1AHTR2BCHRNB2 | |
| SCHEMBL3567539 | 0.80 | HTR6 (0.70) | HTR6HTR7HTR1ADRD2HTR2A | |
| SCHEMBL9903085 | 0.79 | HTR6 (0.57) | HTR6HTR7HTR1AHTR2BCHRNB2 | |
| SCHEMBL9902743 | 0.79 | HTR6 (0.50) | HTR6HTR7HTR1ACHRNB2CHRNA4 | |
| SCHEMBL3136898 | 0.76 | HTR6 (0.60) | HTR6HTR7HTR1AHTR2BDRD2 | |
| SCHEMBL9901916 | 0.75 | HTR3A (0.51) | HTR6HTR7HTR2BDRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1956004-B1 | Quinoline derivatives and their use as 5-HT6 ligands | GLAXO GROUP LTD (GB) | 2012-06-13 | — | — | EP | claimed |