SCHEMBL9905933

SCHEMBL9905933

CCCCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)CCC1COP(=O)(O)O1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.42
ALDH1A1 P00352 5/20 0.42
PPARD Q03181 4/20 0.42
PPARA Q07869 4/20 0.42
F7 P08709 4/20 0.42
F3 P13726 4/20 0.42
FFAR1 O14842 3/20 0.42
KDM4E B2RXH2 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
LMNA P02545 2/20 0.42
CYP3A4 P08684 2/20 0.42
CYP19A1 P11511 2/20 0.42
FABP4 P15090 2/20 0.42
HPGD P15428 2/20 0.42
ALOX15 P16050 2/20 0.42
NR4A2 P43354 2/20 0.42
HSD17B10 Q99714 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
PTGS1 P23219 2/20 0.42
AKR1C3 P42330 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9905947 0.87 ALDH1A1 (0.46) PPARGALDH1A1PPARDPPARAF7
SCHEMBL9905953 0.87 ALDH1A1 (0.43) PPARGALDH1A1PPARDPPARAF7
SCHEMBL9905967 0.82 MGLL (0.45) ALDH1A1MAPTCNR1
SCHEMBL29651433 0.79 LPAR1 (0.52)
SCHEMBL9905954 0.75 MEN1 (0.44) PPARGALDH1A1PPARDPPARAF7
SCHEMBL29372509 0.74 LPAR1 (0.55)
SCHEMBL17482404 0.74 LPAR1 (0.55)
SCHEMBL5963616 0.73 ALDH1A1 (0.39) ALDH1A1
SCHEMBL9905965 0.72 ALDH1A1 (0.55) ALDH1A1CYP3A4ALOX15HSD17B10TDP1
SCHEMBL8009267 0.70 ALDH1A1 (0.71) PPARGALDH1A1PPARDPPARAF7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9925165-B2 Compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof and uses thereof SCF PHARMA INC. (CA) 2018-03-27 US disclosed
US-20170014369-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2017-01-19 US disclosed
US-9480660-B2 Methods for treating inflammatory diseases with compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof SCF PHARMA INC. (CA) 2016-11-01 US disclosed
US-9233915-B2 Polyunsaturated fatty acid monoglycerides, derivatives, and uses thereof SCF PHARMA INC. (CA) 2016-01-12 US disclosed
US-9101563-B2 Method for treating an inflammatory disease with compositions comprising polyunsaturated fatty acid monoglycerides, derivatives thereof and uses thereof SCF PHARMA INC (CA) 2015-08-11 US disclosed
US-20150057348-A1 METHODS FOR TREATING INFLAMMATORY DISEASES WITH COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF CENTRE DE RECHERCHE SUR LES BIOTECHNOLOGIES MARINES (CA) 2015-02-26 US disclosed
US-20140296344-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF CENTRE DE RECHERCHE SUR LES BIOTECHNOLOGIES MARINES (CA) 2014-10-02 US disclosed
US-8816110-B2 Polyunsaturated fatty acid monoglycerides, derivatives, and uses thereof SCF PHARMA INC. (CA) 2014-08-26 US disclosed
US-8722737-B2 Compositions comprising polyunsaturated fatty acid monoglycerides, derivatives thereof and uses thereof SCF PHARMA INC. (CA) 2014-05-13 US disclosed
US-20130059911-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF CENTRE DE RECHERCHE SUR LES BIOTECHNOLOGIES MARINES (CA) 2013-03-07 US disclosed
US-20120213823-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2012-08-23 US disclosed
US-20120213872-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2012-08-23 US disclosed
US-20120208884-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2012-08-16 US disclosed
US-8222295-B2 Compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof and uses thereof CENTRE DE RECHERCHE SUR LES BIOTECHNOLOGIES MARINES (CA) 2012-07-17 US disclosed
US-8198324-B2 Compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof and uses thereof CENTRE DE RECHERCHE SUR LES BIOTECHNOLOGIES MARINES (CA) 2012-06-12 US disclosed
US-8119690-B2 Polyunsaturated fatty acid monoglycerides, derivatives, and uses thereof CENTRE DE RECHERCHE SUR LES BIOTECHNOLOGIES MARINES (CA) 2012-02-21 US disclosed
US-20100196496-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2010-08-05 US disclosed
US-20100160261-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF SCF PHARMA INC. (CA) 2010-06-24 US disclosed
US-20090292019-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF SCF PHARMA INC. (CA) 2009-11-26 US disclosed
US-20090291102-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2009-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120213872-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES THEREOF AND USES THEREOF MGLL, PNLIP, FASN PPARG 55/4885ALDH1A1 1011/4885PPARD 209/4885
US-20130059911-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF FASN, MGLL, FADS1 PPARG 46/4885ALDH1A1 695/4885PPARD 108/4885
US-20100196496-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF MGLL, PNLIP, FASN PPARG 47/4885ALDH1A1 1033/4885PPARD 207/4885
US-20120208884-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES THEREOF AND USES THEREOF MGLL, PNLIP, FASN PPARG 55/4885ALDH1A1 1011/4885PPARD 209/4885
US-20150057348-A1 METHODS FOR TREATING INFLAMMATORY DISEASES WITH COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF PPARG, PTGES, PTGIS PPARG 1/4885ALDH1A1 1362/4885PPARD 27/4885
US-20090292019-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF FASN, MGLL, FADS1 PPARG 46/4885ALDH1A1 695/4885PPARD 108/4885
US-20170014369-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF PPARG, PTGES, PTGIS PPARG 1/4885ALDH1A1 1476/4885PPARD 36/4885
US-20140296344-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF FASN, MGLL, FADS1 PPARG 46/4885ALDH1A1 695/4885PPARD 108/4885
US-20090291102-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF MGLL, PNLIP, FASN PPARG 47/4885ALDH1A1 1033/4885PPARD 207/4885
US-20120213823-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES THEREOF AND USES THEREOF MGLL, PNLIP, FASN PPARG 55/4885ALDH1A1 1011/4885PPARD 209/4885
US-20100160261-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF FASN, MGLL, FADS1 PPARG 46/4885ALDH1A1 695/4885PPARD 108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.