SCHEMBL9905947

SCHEMBL9905947

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)CCC1COP(=O)(O)O1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
F7 P08709 4/20 0.46
F3 P13726 4/20 0.46
CYP19A1 P11511 4/20 0.46
CYP3A4 P08684 3/20 0.46
ALOX15 P16050 3/20 0.46
HSD17B10 Q99714 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
PTGS1 P23219 3/20 0.46
PPARG P37231 3/20 0.46
PPARD Q03181 3/20 0.46
PPARA Q07869 3/20 0.46
MAPT P10636 2/20 0.46
OXER1 Q8TDS5 2/20 0.46
KMT2A Q03164 2/20 0.46
KDM4E B2RXH2 2/20 0.46
FFAR1 O14842 2/20 0.46
LMNA P02545 2/20 0.46
HPGD P15428 2/20 0.46
FFAR4 Q5NUL3 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9905953 0.95 ALDH1A1 (0.43) ALDH1A1F7F3CYP19A1CYP3A4
SCHEMBL9905933 0.87 PPARG (0.42) ALDH1A1F7F3CYP19A1CYP3A4
SCHEMBL9905965 0.82 ALDH1A1 (0.55) ALDH1A1CYP3A4ALOX15HSD17B10TDP1
SCHEMBL9905963 0.77 ADORA3 (0.53) ALDH1A1F7F3CYP19A1CYP3A4
SCHEMBL9905959 0.76 ALDH1A1 (0.47) ALDH1A1F7F3CYP19A1CYP3A4
SCHEMBL17744004 0.75 ALDH1A1 (0.76) ALDH1A1F7F3CYP19A1CYP3A4
SCHEMBL17744002 0.75 ALDH1A1 (0.76) ALDH1A1F7F3CYP19A1CYP3A4
SCHEMBL11913792 0.75 ALDH1A1 (0.76) ALDH1A1F7F3CYP19A1CYP3A4
SCHEMBL9905968 0.74 NR1I2 (0.43) ALDH1A1CYP19A1CYP3A4ALOX15HSD17B10
SCHEMBL9905967 0.72 MGLL (0.45) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9925165-B2 Compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof and uses thereof SCF PHARMA INC. (CA) 2018-03-27 US disclosed
US-20170014369-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2017-01-19 US disclosed
US-9480660-B2 Methods for treating inflammatory diseases with compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof SCF PHARMA INC. (CA) 2016-11-01 US disclosed
US-9233915-B2 Polyunsaturated fatty acid monoglycerides, derivatives, and uses thereof SCF PHARMA INC. (CA) 2016-01-12 US disclosed
US-9101563-B2 Method for treating an inflammatory disease with compositions comprising polyunsaturated fatty acid monoglycerides, derivatives thereof and uses thereof SCF PHARMA INC (CA) 2015-08-11 US disclosed
US-20150057348-A1 METHODS FOR TREATING INFLAMMATORY DISEASES WITH COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF CENTRE DE RECHERCHE SUR LES BIOTECHNOLOGIES MARINES (CA) 2015-02-26 US disclosed
US-20140296344-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF CENTRE DE RECHERCHE SUR LES BIOTECHNOLOGIES MARINES (CA) 2014-10-02 US disclosed
US-8816110-B2 Polyunsaturated fatty acid monoglycerides, derivatives, and uses thereof SCF PHARMA INC. (CA) 2014-08-26 US disclosed
US-8722737-B2 Compositions comprising polyunsaturated fatty acid monoglycerides, derivatives thereof and uses thereof SCF PHARMA INC. (CA) 2014-05-13 US disclosed
US-20130059911-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF CENTRE DE RECHERCHE SUR LES BIOTECHNOLOGIES MARINES (CA) 2013-03-07 US disclosed
US-20120213823-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2012-08-23 US disclosed
US-20120213872-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2012-08-23 US disclosed
US-20120208884-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2012-08-16 US disclosed
US-8222295-B2 Compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof and uses thereof CENTRE DE RECHERCHE SUR LES BIOTECHNOLOGIES MARINES (CA) 2012-07-17 US disclosed
US-8198324-B2 Compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof and uses thereof CENTRE DE RECHERCHE SUR LES BIOTECHNOLOGIES MARINES (CA) 2012-06-12 US disclosed
US-8119690-B2 Polyunsaturated fatty acid monoglycerides, derivatives, and uses thereof CENTRE DE RECHERCHE SUR LES BIOTECHNOLOGIES MARINES (CA) 2012-02-21 US disclosed
US-20100196496-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2010-08-05 US disclosed
US-20100160261-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF SCF PHARMA INC. (CA) 2010-06-24 US disclosed
US-20090291102-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2009-11-26 US disclosed
US-20090292019-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF SCF PHARMA INC. (CA) 2009-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120213872-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES THEREOF AND USES THEREOF MGLL, PNLIP, FASN ALDH1A1 1011/4885F7 3563/4885F3 2723/4885
US-20130059911-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF FASN, MGLL, FADS1 ALDH1A1 695/4885F7 4842/4885F3 3366/4885
US-20100196496-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF MGLL, PNLIP, FASN ALDH1A1 1033/4885F7 3411/4885F3 2727/4885
US-20120208884-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES THEREOF AND USES THEREOF MGLL, PNLIP, FASN ALDH1A1 1011/4885F7 3563/4885F3 2723/4885
US-20150057348-A1 METHODS FOR TREATING INFLAMMATORY DISEASES WITH COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF PPARG, PTGES, PTGIS ALDH1A1 1362/4885F7 3869/4885F3 2487/4885
US-20090292019-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF FASN, MGLL, FADS1 ALDH1A1 695/4885F7 4842/4885F3 3366/4885
US-20170014369-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF PPARG, PTGES, PTGIS ALDH1A1 1476/4885F7 2686/4885F3 1322/4885
US-20140296344-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF FASN, MGLL, FADS1 ALDH1A1 695/4885F7 4842/4885F3 3366/4885
US-20090291102-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF MGLL, PNLIP, FASN ALDH1A1 1033/4885F7 3411/4885F3 2727/4885
US-20120213823-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES THEREOF AND USES THEREOF MGLL, PNLIP, FASN ALDH1A1 1011/4885F7 3563/4885F3 2723/4885
US-20100160261-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF FASN, MGLL, FADS1 ALDH1A1 695/4885F7 4842/4885F3 3366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.