SCHEMBL9905958

SCHEMBL9905958

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OCC1COS(=O)(=O)O1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 2/20 0.54
NR1I2 O75469 1/20 0.54
PGR P06401 1/20 0.54
PTGS2 P35354 1/20 0.54
PDE4D Q08499 1/20 0.54
ALDH1A1 P00352 2/20 0.49
CYP3A4 P08684 1/20 0.49
ALOX15 P16050 1/20 0.49
TSHR P16473 1/20 0.49
HSD17B10 Q99714 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
F7 P08709 1/20 0.43
CYP19A1 P11511 1/20 0.43
F3 P13726 1/20 0.43
RXRA P19793 1/20 0.43
PTGS1 P23219 1/20 0.43
PPARG P37231 1/20 0.43
KMT2A Q03164 1/20 0.43
PPARD Q03181 1/20 0.43
PPARA Q07869 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9905971 0.95 ALDH1A1 (0.56) ADORA3NR1I2PGRPTGS2PDE4D
SCHEMBL9905969 0.93 NR1I2 (0.44) ADORA3NR1I2PGRPTGS2PDE4D
SCHEMBL9905972 0.87 MGLL (0.46) ALDH1A1
SCHEMBL9905939 0.81 ALDH1A1 (0.44) ADORA3NR1I2PGRPTGS2PDE4D
SCHEMBL471877 0.79 ALDH1A1 (0.66) ADORA3NR1I2PGRPTGS2PDE4D
SCHEMBL9905959 0.77 ALDH1A1 (0.47) ADORA3NR1I2PTGS2ALDH1A1CYP3A4
SCHEMBL9905956 0.77 NR1I2 (0.54) ADORA3NR1I2PGRPTGS2PDE4D
SCHEMBL22399985 0.77 NR1I2 (0.54) ADORA3NR1I2PGRPTGS2PDE4D
SCHEMBL9905963 0.76 ADORA3 (0.53) ADORA3NR1I2PGRPTGS2PDE4D
SCHEMBL9905938 0.76 ALDH1A1 (0.42) ADORA3NR1I2PGRPTGS2PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9925165-B2 Compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof and uses thereof SCF PHARMA INC. (CA) 2018-03-27 US disclosed
US-9925165-B2 Compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof and uses thereof SCF PHARMA INC. (CA) 2018-03-27 US disclosed
US-20170014369-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2017-01-19 US disclosed
US-20170014369-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2017-01-19 US disclosed
US-9480660-B2 Methods for treating inflammatory diseases with compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof SCF PHARMA INC. (CA) 2016-11-01 US disclosed
US-9480660-B2 Methods for treating inflammatory diseases with compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof SCF PHARMA INC. (CA) 2016-11-01 US disclosed
US-9233915-B2 Polyunsaturated fatty acid monoglycerides, derivatives, and uses thereof SCF PHARMA INC. (CA) 2016-01-12 US disclosed
US-9233915-B2 Polyunsaturated fatty acid monoglycerides, derivatives, and uses thereof SCF PHARMA INC. (CA) 2016-01-12 US disclosed
EP-2121576-B1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF CT DE RECH SUR LES BIOTECHNOLOGIES MARINE (CA) 2015-11-11 EP disclosed
US-9101563-B2 Method for treating an inflammatory disease with compositions comprising polyunsaturated fatty acid monoglycerides, derivatives thereof and uses thereof SCF PHARMA INC (CA) 2015-08-11 US disclosed
US-20100196496-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2010-08-05 US disclosed
US-20100196496-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2010-08-05 US disclosed
US-20100160261-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF SCF PHARMA INC. (CA) 2010-06-24 US disclosed
US-20100160261-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF SCF PHARMA INC. (CA) 2010-06-24 US disclosed
US-20090291102-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2009-11-26 US disclosed
US-20090291102-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF SCF PHARMA INC. (CA) 2009-11-26 US disclosed
US-20090292019-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF SCF PHARMA INC. (CA) 2009-11-26 US disclosed
US-20090292019-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF SCF PHARMA INC. (CA) 2009-11-26 US disclosed
WO-2008113177-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF CENTRE DE RECHERCHE SUR LES BIOTECHNOLOGIES MARINES (CA) 2008-09-25 WO disclosed
WO-2008098375-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF CENTRE DE RECHERCHE SUR LES BIOTECHNOLOGIES MARINES (CA) 2008-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100196496-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF MGLL, PNLIP, FASN ADORA3 1612/4885NR1I2 2216/4885PGR 1737/4885
US-20090292019-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF FASN, MGLL, FADS1 ADORA3 2402/4885NR1I2 1180/4885PGR 2272/4885
US-20170014369-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF PPARG, PTGES, PTGIS ADORA3 1724/4885NR1I2 2641/4885PGR 4113/4885
US-20090291102-A1 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF MGLL, PNLIP, FASN ADORA3 1612/4885NR1I2 2216/4885PGR 1737/4885
US-20100160261-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF FASN, MGLL, FADS1 ADORA3 2402/4885NR1I2 1180/4885PGR 2272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.