Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820950 | 0.81 | NPSR1 (0.41) | L3MBTL1LMNATHRBHPGDNPSR1 | |
| SCHEMBL467007 | 0.77 | LMNA (0.53) | L3MBTL1LMNATHRBHPGDNPSR1 | |
| SCHEMBL7467929 | 0.74 | ALDH1A1 (0.77) | L3MBTL1NPSR1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL11195264 | 0.71 | ALDH1A1 (0.83) | L3MBTL1HPGDNPSR1ALDH1A1POLB | |
| SCHEMBL24937727 | 0.71 | NPSR1 (0.50) | L3MBTL1LMNATHRBHPGDNPSR1 | |
| SCHEMBL19778 | 0.71 | NPSR1 (0.70) | L3MBTL1HPGDNPSR1ALDH1A1POLB | |
| SCHEMBL812818 | 0.71 | NPSR1 (1.00) | L3MBTL1HPGDNPSR1ALDH1A1POLB | |
| SCHEMBL28394067 | 0.70 | TSHR (0.57) | L3MBTL1LMNATHRBHPGDNPSR1 | |
| SCHEMBL9546821 | 0.70 | L3MBTL1 (0.45) | L3MBTL1LMNATHRBHPGDNPSR1 | |
| SCHEMBL11661567 | 0.69 | ALDH1A1 (0.87) | L3MBTL1HPGDNPSR1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198487-B2 | Method for lithium exchange reactions | LONZA AG (CH) | 2012-06-12 | — | — | US | disclosed |
| US-20100113839-A1 | METHOD FOR LITHIUM EXCHANGE REACTIONS | LONZA AG (CH) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113839-A1 | METHOD FOR LITHIUM EXCHANGE REACTIONS | SLC6A5, SLC6A9, SLC6A6 | L3MBTL1 2788/4885LMNA 1170/4885THRB 3707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.