Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.52 |
| ▸ | KDM5A | P29375 | 1/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.42 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.42 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9907394 | 0.87 | CSNK2A2 (0.43) | KDM4CKDM5AKDM5BCSNK2A2CSNK2B | |
| SCHEMBL9907404 | 0.85 | ALOX15 (0.52) | KDM4CKDM5AKDM5BPLA2G7MEN1 | |
| SCHEMBL9909213 | 0.83 | KDM4C (0.46) | KDM4CMAPK1TTRKDM4E | |
| SCHEMBL9907326 | 0.82 | PIK3CA (0.57) | KDM4CKDM5AKDM5BMEN1KMT2A | |
| SCHEMBL9907817 | 0.82 | HTR5A (0.53) | — | |
| SCHEMBL21083359 | 0.81 | TGFBR1 (0.51) | KDM4C | |
| SCHEMBL4641324 | 0.81 | TDP1 (0.50) | KDM4CKDM5AKDM5BMEN1KMT2A | |
| SCHEMBL9907345 | 0.80 | KDM4C (0.41) | KDM4CKDM5AKDM5BMEN1KMT2A | |
| SCHEMBL9909203 | 0.80 | ALDH1A1 (0.41) | KDM4CIP6K1IP6K3IP6K2ALDH1A1 | |
| SCHEMBL9907407 | 0.80 | CYP19A1 (0.38) | KDM4CKDM5AKDM5BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853242-B2 | Nitrogenous-ring acylguanidine derivative | ASTELLAS PHARMA INC. (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20120142727-A1 | NITROGENOUS-RING ACYLGUANIDINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142727-A1 | NITROGENOUS-RING ACYLGUANIDINE DERIVATIVE | HTR5A, HTR2A, HTR1E | KDM4C 1366/4885KDM5A 172/4885KDM5B 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.