Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924132 | 0.87 | NPC1 (0.39) | TRPV1DRD2HTR2ADRD3HSD17B10 | |
| SCHEMBL9924231 | 0.85 | LMNA (0.41) | TRPV1DRD2PTGS1MAPK11MAPK14 | |
| SCHEMBL17206623 | 0.84 | TRPV1 (0.38) | TRPV1HSD17B10NPC1RAB9AKMT2A | |
| SCHEMBL9924153 | 0.82 | TRPV1 (0.42) | TRPV1MAPK11MAPK14EPHX2MRGPRX4 | |
| SCHEMBL9924227 | 0.80 | EPHX2 (0.52) | PTGS1EPHX2MEN1KMT2A | |
| SCHEMBL9939456 | 0.78 | SLC9A1 (0.36) | TRPV1SLC9A1HSD17B10PTGS1DHODH | |
| SCHEMBL9924262 | 0.77 | UBE2M (0.46) | TRPV1PTGS1EPHX2MRGPRX4MEN1 | |
| SCHEMBL17206700 | 0.75 | EPHX2 (0.47) | TRPV1EPHX2 | |
| SCHEMBL9924283 | 0.75 | NPC1 (0.45) | HSD17B10EPHX2MEN1NPC1RAB9A | |
| SCHEMBL17206709 | 0.74 | TRPV1 (0.42) | TRPV1EPHX2MRGPRX4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| WO-2012078867-A2 | CYCLOALKYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |