Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8956095 | 0.84 | TSHR (0.46) | TSHRALDH1A1THRBMMP8 | |
| SCHEMBL9639494 | 0.81 | TSHR (0.41) | TSHRALDH1A1MMP8 | |
| SCHEMBL1898448 | 0.77 | ALDH1A1 (0.42) | TSHRALDH1A1THRB | |
| SCHEMBL308148 | 0.76 | MMP8 (0.36) | MMP8 | |
| SCHEMBL14543776 | 0.75 | TSHR (0.44) | TSHRALDH1A1THRBMMP8 | |
| Methacrylic Acid SCHEMBL8956104 | 0.72 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL31539522 | 0.72 | TSHR (0.39) | TSHRALDH1A1THRB | |
| SCHEMBL23494139 | 0.72 | TSHR (0.44) | TSHRALDH1A1THRB | |
| SCHEMBL23494347 | 0.72 | TSHR (0.48) | TSHRALDH1A1THRBMMP8 | |
| SCHEMBL6858215 | 0.71 | LMNA (0.39) | ALDH1A1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809447-B2 | Acetoacetate-functional monomers and their uses in coating compositions | EASTMAN CHEMICAL COMPANY (US) | 2014-08-19 | — | — | US | disclosed |
| EP-2651874-A1 | ACETOACETATE-FUNCTIONAL MONOMERS AND THEIR USES IN COATING COMPOSITIONS | Eastman Chemical Company (US) | 2013-10-23 | — | — | EP | disclosed |
| US-20120157610-A1 | ACETOACETATE-FUNCTIONAL MONOMERS AND THEIR USES IN COATING COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2012-06-21 | — | — | US | disclosed |
| WO-2012082348-A1 | ACETOACETATE-FUNCTIONAL MONOMERS AND THEIR USES IN COATING COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157610-A1 | ACETOACETATE-FUNCTIONAL MONOMERS AND THEIR USES IN COATING COMPOSITIONS | ACACA, AMD1, ACAT2 | TSHR 4616/4885ALDH1A1 17/4885THRB 2391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.