Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 20/20 | 0.78 |
| ▸ | HTR2A | P28223 | 20/20 | 0.78 |
| ▸ | DRD3 | P35462 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9933617 | 1.00 | DRD2 (0.78) | DRD2HTR2ADRD3 | |
| SCHEMBL13584122 | 0.88 | DRD2 (0.78) | DRD2HTR2ADRD3 | |
| SCHEMBL13584120 | 0.88 | DRD2 (0.78) | DRD2HTR2ADRD3 | |
| SCHEMBL9933709 | 0.88 | DRD2 (1.00) | DRD2HTR2ADRD3 | |
| SCHEMBL9933708 | 0.88 | DRD2 (1.00) | DRD2HTR2ADRD3 | |
| SCHEMBL9933350 | 0.86 | DRD2 (1.00) | DRD2HTR2ADRD3 | |
| SCHEMBL9933353 | 0.86 | DRD2 (1.00) | DRD2HTR2ADRD3 | |
| SCHEMBL9934155 | 0.86 | DRD2 (1.00) | DRD2HTR2ADRD3 | |
| SCHEMBL9934158 | 0.86 | DRD2 (1.00) | DRD2HTR2ADRD3 | |
| SCHEMBL9933387 | 0.84 | DRD2 (1.00) | DRD2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268375-B1 | PHOTOCHROMIC THIENOCHROMENE COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2022-06-15 | — | — | EP | disclosed |
| EP-3071576-B9 | PHOTOCHROMIC INDENO-FUSED RING PYRAN COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2021-12-22 | — | — | EP | disclosed |
| US-20210317129-A1 | Indolenaphthopyrans | TRANSITIONS OPTICAL, LTD. (IE) | 2021-10-14 | — | — | US | disclosed |
| EP-3071576-B1 | PHOTOCHROMIC INDENO-FUSED RING PYRAN COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2021-08-18 | — | — | EP | disclosed |
| CN-113150007-A | Photochromic indeno-fused ring pyran compounds | 光学转变公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-107406459-B | Photochromic thienobenzopyran compounds | 光学转变公司 | 2021-06-08 | — | — | CN | disclosed |
| CN-109096088-B | Process for preparing fused ring indeno compounds | 光学转变公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-105829283-B | Fused ring indeno compounds for preparing photochromic compounds | 光学转变公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-105849089-B | Process for preparing fused ring indeno compounds | 光学转变公司 | 2020-10-09 | — | — | CN | disclosed |
| EP-3071550-B1 | METHOD OF PREPARING FUSED RING INDENO COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2019-03-13 | — | — | EP | disclosed |
| WO-2015077147-A1 | METHOD OF PREPARING FUSED RING INDENO COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2015-05-28 | — | — | WO | disclosed |
| WO-2015077141-A1 | FUSED RING INDENO COMPOUNDS FOR PREPARATION OF PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2015-05-28 | — | — | WO | disclosed |
| WO-2015077264-A1 | PHOTOCHROMIC INDENO-FUSED RING PYRAN COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2015-05-28 | — | — | WO | disclosed |
| US-20150141661-A1 | Photochromic Indeno-Fused Ring Pyran Compounds | TRANSITIONS OPTICAL, INC. (US) | 2015-05-21 | — | — | US | disclosed |
| US-20150141662-A1 | Method Of Preparing Fused Ring Indeno Compounds | TRANSITIONS OPTICAL, INC. (US) | 2015-05-21 | — | — | US | disclosed |
| US-20150141663-A1 | Fused Ring Indeno Compounds For Preparation Of Photochromic Compounds | TRANSITIONS OPTICAL, INC. (US) | 2015-05-21 | — | — | US | disclosed |
| EP-2651914-B1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2015-05-13 | — | — | EP | disclosed |
| US-9029565-B1 | Fused ring indeno compounds for preparation of photochromic compounds | TRANSITIONS OPTICAL, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-8920928-B2 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-20120156508-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141662-A1 | Method Of Preparing Fused Ring Indeno Compounds | INHA, INTS9, CA9 | DRD2 3394/4885HTR2A 3539/4885DRD3 2148/4885 |
| US-20150141663-A1 | Fused Ring Indeno Compounds For Preparation Of Photochromic Compounds | IPO5, INCENP, NQO1 | DRD2 2024/4885HTR2A 1223/4885DRD3 1264/4885 |
| US-20210317129-A1 | Indolenaphthopyrans | AHR, TDO2, TPH2 | DRD2 455/4885HTR2A 76/4885DRD3 159/4885 |
| US-20150141661-A1 | Photochromic Indeno-Fused Ring Pyran Compounds | INF2, INCENP, RB1 | DRD2 557/4885HTR2A 535/4885DRD3 68/4885 |
| US-20120156508-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | CRY2, CRY1, IPO4 | DRD2 2059/4885HTR2A 478/4885DRD3 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.