Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.76 |
| ▸ | TSHR | P16473 | 3/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.76 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | THRB | P10828 | 3/20 | 0.59 |
| ▸ | RECQL | P46063 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 7/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9933293 | 0.94 | ALDH1A1 (0.85) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL6328763 | 0.93 | ALDH1A1 (0.90) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL144947 | 0.87 | ALDH1A1 (0.73) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL2720733 | 0.86 | ALDH1A1 (0.73) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL39447 | 0.86 | ALDH1A1 (1.00) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL15476044 | 0.86 | ALDH1A1 (1.00) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL31215174 | 0.86 | ALDH1A1 (1.00) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL16962433 | 0.85 | ALDH1A1 (0.71) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL9934007 | 0.82 | TDP1 (0.81) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL25411983 | 0.82 | ALDH1A1 (0.67) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835687-B2 | Method for preparation of 4,4′-dinitrodiphenylamine and 4,4′-bis(alkylamino)diphenylamine with the base catalyst complex | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2014-09-16 | — | — | US | disclosed |
| US-8759587-B2 | Method for preparation of 4,4′-dinitrodiphenylamine and 4,4′-bis(alkylamino)diphenylamine by using 4-nitroaniline | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2014-06-24 | — | — | US | disclosed |
| US-20120197044-A1 | PRODUCTION METHOD FOR 4,4'-BIS(ALKYLAMINO) DIPHENYLAMINE | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2012-08-02 | — | — | US | disclosed |
| US-20120157713-A1 | METHOD FOR PREPARATION OF 4,4'-DINITRODIPHENYLAMINE AND 4,4'-BIS(ALKYLAMINO)DIPHENYLAMINE WITH THE BASE CATALYST COMPLEX | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2012-06-21 | — | — | US | disclosed |
| US-20120157714-A1 | METHOD FOR PREPARATION OF 4,4'-DINITRODIPHENYLAMINE AND 4,4'-BIS(ALKYLAMINO)DIPHENYLAMINE BY USING 4-NITROANILINE | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157714-A1 | METHOD FOR PREPARATION OF 4,4'-DINITRODIPHENYLAMINE AND 4,4'-BIS(ALKYLAMINO)DIPHENYLAMINE BY USING 4-NITROANILINE | NAAA, AADAT, HPD | ALDH1A1 429/4885CYP3A4 37/4885ALOX15 1089/4885 |
| US-20120157713-A1 | METHOD FOR PREPARATION OF 4,4'-DINITRODIPHENYLAMINE AND 4,4'-BIS(ALKYLAMINO)DIPHENYLAMINE WITH THE BASE CATALYST COMPLEX | NAAA, HNF4A, ABAT | ALDH1A1 845/4885CYP3A4 157/4885ALOX15 1651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.