SCHEMBL9936240

SCHEMBL9936240

CC(C)(C=O)CNCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.50
MEN1 O00255 4/20 0.50
ADH1B P00325 1/20 0.48
ADH1C P00326 1/20 0.48
ADH1A P07327 1/20 0.48
ADH7 P40394 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MAOA P21397 1/20 0.44
LMNA P02545 1/20 0.44
RAB9A P51151 1/20 0.44
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
MAPT P10636 2/20 0.42
GAA P10253 2/20 0.42
CHRM2 P08172 1/20 0.42
RIPK1 Q13546 1/20 0.42
KDM4E B2RXH2 2/20 0.42
CYP3A4 P08684 1/20 0.42
MITF O75030 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL340998 0.81 SIGMAR1 (0.48) KMT2AMEN1TDP1MAOALMNA
SCHEMBL5461543 0.79 MEN1 (0.56) KMT2AMEN1ADH1BADH1CADH1A
SCHEMBL340965 0.77 LMNA (0.52) ADH1BADH1CADH1AADH7LMNA
SCHEMBL15114181 0.76 MEN1 (0.58) KMT2AMEN1TDP1MAOALMNA
SCHEMBL4588005 0.76 MEN1 (0.52) KMT2AMEN1ADH1BADH1CADH1A
SCHEMBL3926325 0.76 SLC6A2 (0.54) KMT2AMEN1TDP1MAOAMAPT
SCHEMBL2013167 0.76 MEN1 (0.57) KMT2AMEN1TDP1MAOALMNA
SCHEMBL13731240 0.76 RIPK1 (0.53) KMT2AMEN1TDP1LMNARAB9A
SCHEMBL96457 0.75 TAAR1 (0.52) KMT2AMEN1ADH1BADH1CADH1A
SCHEMBL23474625 0.74 MEN1 (0.50) KMT2AMEN1ADH1BADH1CADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2651876-B1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECH AG (CH) 2017-08-09 EP claimed
CN-103313995-B Secondary aminosilanes SIKA技术股份公司 2016-08-10 CN claimed
CN-103261146-B Polyamines having secondary aliphatic amino groups SIKA TECHNOLOGY AG (CH) 2016-01-27 CN claimed
US-8877955-B2 Secondary aminosilanes SIKA TECHNOLOGY AG (CH) 2014-11-04 US claimed
US-20130281562-A1 SECONDARY AMINOSILANES SIKA TECHNOLOGY AG (CH) 2013-10-24 US claimed
EP-2651876-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS Sika Technology AG (CH) 2013-10-23 EP claimed
EP-2651956-A1 SECONDARY AMINOSILANES Sika Technology AG (CH) 2013-10-23 EP claimed
US-20130261270-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECHNOLOGY AG (CH) 2013-10-03 US claimed
CN-103313995-A Secondary aminosilanes SIKA TECHNOLOGY AG 2013-09-18 CN claimed
CN-103261146-A Polyamines having secondary aliphatic amino groups SIKA TECHNOLOGY AG 2013-08-21 CN claimed
EP-2468759-A1 Secondary Aminosilanes Sika Technology AG (CH) 2012-06-27 EP claimed
WO-2012080266-A1 SECONDARY AMINOSILANES SIKA TECHNOLOGY AG (CH) 2012-06-21 WO claimed
WO-2012080265-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECHNOLOGY AG (CH) 2012-06-21 WO claimed
EP-2465843-A1 Polyamines with secondary aliphatic amines Sika Technology AG (CH) 2012-06-20 EP claimed
EP-3484898-B1 METHOD OF STABILIZING IMINO-FUNCTIONAL SILANE MOMENTIVE PERFORMANCE MAT INC (US) 2023-06-28 EP disclosed
EP-4053134-A1 METHOD OF STABILIZING IMINO-FUNCTIONAL SILANE Momentive Performance Materials Inc. (US) 2022-09-07 EP disclosed
CN-109563232-B Two-component polyurethane adhesive with mechanical properties substantially unaffected by temperature and high strength SIKA技术股份公司 2022-04-12 CN disclosed
WO-2012080266-A1 SECONDARY AMINOSILANES SIKA TECHNOLOGY AG (CH) 2012-06-21 WO disclosed
WO-2012080265-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECHNOLOGY AG (CH) 2012-06-21 WO disclosed
EP-2465843-A1 Polyamines with secondary aliphatic amines Sika Technology AG (CH) 2012-06-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130281562-A1 SECONDARY AMINOSILANES AS3MT, SRM, MSN KMT2A 293/4885MEN1 2889/4885ADH1B 4383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.