Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96457 | 0.79 | TAAR1 (0.52) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL15387143 | 0.77 | LMNA (0.57) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL9936240 | 0.77 | KMT2A (0.50) | LMNACYP3A4ADH1BADH1CADH1A | |
| SCHEMBL165251 | 0.74 | LMNA (0.59) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL340998 | 0.74 | SIGMAR1 (0.48) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL14161468 | 0.74 | LMNA (0.63) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL11818840 | 0.74 | LMNA (0.63) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL2444854 | 0.73 | LMNA (0.57) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL28416740 | 0.71 | TAAR1 (0.52) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL8613504 | 0.71 | LMNA (0.65) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651876-B1 | POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECH AG (CH) | 2017-08-09 | — | — | EP | claimed |
| US-8877955-B2 | Secondary aminosilanes | SIKA TECHNOLOGY AG (CH) | 2014-11-04 | — | — | US | claimed |
| US-20130281562-A1 | SECONDARY AMINOSILANES | SIKA TECHNOLOGY AG (CH) | 2013-10-24 | — | — | US | claimed |
| EP-2651876-A1 | POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | Sika Technology AG (CH) | 2013-10-23 | — | — | EP | claimed |
| US-20130261270-A1 | POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2013-10-03 | — | — | US | claimed |
| EP-2468759-A1 | Secondary Aminosilanes | Sika Technology AG (CH) | 2012-06-27 | — | — | EP | claimed |
| WO-2012080265-A1 | POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2012-06-21 | — | — | WO | claimed |
| EP-2465843-A1 | Polyamines with secondary aliphatic amines | Sika Technology AG (CH) | 2012-06-20 | — | — | EP | claimed |
| EP-3484898-B1 | METHOD OF STABILIZING IMINO-FUNCTIONAL SILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2023-06-28 | — | — | EP | disclosed |
| EP-4053134-A1 | METHOD OF STABILIZING IMINO-FUNCTIONAL SILANE | Momentive Performance Materials Inc. (US) | 2022-09-07 | — | — | EP | disclosed |
| US-11230563-B2 | Method of stabilizing imino-functional silane | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2022-01-25 | — | — | US | disclosed |
| US-11149106-B2 | Two-component polyurethane adhesive having substantially temperature-independent mechanical properties and high strength | SIKA TECHNOLOGY AG (CH) | 2021-10-19 | — | — | US | disclosed |
| US-20210309787-A1 | POLYURETHANE COMPOSITION HAVING A LOW CONTENT OF MONOMERIC DIISOCYANTES | SIKA TECHNOLOGY AG (CH) | 2021-10-07 | — | — | US | disclosed |
| EP-3833701-A1 | POLYURETHANE COMPOSITION HAVING A LOW CONTENT OF MONOMERIC DIISOCYANTES | Sika Technology AG (CH) | 2021-06-16 | — | — | EP | disclosed |
| EP-2236535-A1 | Humidity curing polyurethane composition being accelerated by influence of heat | Sika Technology AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| EP-2236533-A1 | Heat curing or heat activatable composition comprising a surface deactivated polyisocyanate | Sika Technology AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| US-20100101455-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2010-04-29 | — | — | US | disclosed |
| EP-2178828-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE | Sika Technology AG (CH) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009010522-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE | SIKA TECHNOLOGY AG (CH) | 2009-01-22 | — | — | WO | disclosed |
| EP-2017260-A1 | Aldimines and compounds containing aldimine | Sika Technology AG (CH) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11230563-B2 | Method of stabilizing imino-functional silane | INF2, RNF168, BOLA2; BOLA2B | LMNA 192/4885CYP2D6 4062/4885CYP3A4 3692/4885 |
| US-20130281562-A1 | SECONDARY AMINOSILANES | AS3MT, SRM, MSN | LMNA 3044/4885CYP2D6 4677/4885CYP3A4 4411/4885 |
| US-20100101455-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | ALDH7A1, ILK, ALDH3A1 | LMNA 404/4885CYP2D6 2241/4885CYP3A4 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.