Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16459222 | 0.86 | OPRK1 (0.40) | BCHEDRD2DRD4MAOB | |
| SCHEMBL9937907 | 0.85 | AGTR2 (0.46) | BCHEDRD2DRD4MAOBAGTR2 | |
| SCHEMBL9937434 | 0.73 | CHRM2 (0.37) | BCHEAGTR2CHRM2CHRM4CHRM5 | |
| SCHEMBL375867 | 0.73 | CHRM3 (0.35) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL211059 | 0.73 | DRD2 (0.43) | BCHEDRD2DRD4AGTR2FAAH | |
| SCHEMBL1411328 | 0.73 | KLK7 (0.44) | BCHEMAOBAGTR2L3MBTL1 | |
| SCHEMBL4756430 | 0.71 | FAAH (0.52) | FAAHL3MBTL1 | |
| SCHEMBL12810017 | 0.70 | KLK7 (0.42) | BCHEMAOBAGTR2L3MBTL1 | |
| SCHEMBL16459394 | 0.70 | BCHE (0.40) | BCHEDRD2DRD4MAOBFAAH | |
| SCHEMBL9942316 | 0.70 | KLK7 (0.37) | BCHEMAOBAGTR2ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651454-A1 | IMAGING AGENTS | Chroma Therapeutics Ltd. (GB) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080705-A1 | IMAGING AGENTS | CHROMA THERAPEUTICS LTD (GB) | 2012-06-21 | — | — | WO | disclosed |