Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9937901 | 0.85 | BCHE (0.43) | AGTR2BCHEDRD2DRD4MAOB | |
| SCHEMBL16459222 | 0.82 | OPRK1 (0.40) | BCHEDRD2DRD4MAOB | |
| SCHEMBL375868 | 0.73 | TPSAB1 (0.36) | AGTR2PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL9937440 | 0.71 | PRSS1 (0.39) | AGTR2BCHEF2PRSS1TPSAB1 | |
| SCHEMBL14917669 | 0.70 | AGTR2 (0.62) | AGTR2BCHE | |
| SCHEMBL28633819 | 0.69 | BCHE (0.48) | BCHEDRD2DRD4 | |
| SCHEMBL1411328 | 0.69 | KLK7 (0.44) | AGTR2BCHEMAOB | |
| SCHEMBL211059 | 0.68 | DRD2 (0.43) | AGTR2BCHEDRD2DRD4FAAH | |
| SCHEMBL565036 | 0.68 | AGTR2 (0.60) | AGTR2 | |
| SCHEMBL1634212 | 0.68 | AGTR2 (0.60) | AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651454-A1 | IMAGING AGENTS | Chroma Therapeutics Ltd. (GB) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080705-A1 | IMAGING AGENTS | CHROMA THERAPEUTICS LTD (GB) | 2012-06-21 | — | — | WO | disclosed |