Ethyl Acetate

Ethyl Acetate

SCHEMBL9938554

CCOC(C)=O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Ethyl Acetate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM5 known ✓ P08912 2/20 0.42
CHRM1 known ✓ P11229 2/20 0.42
CHRM3 known ✓ P20309 2/20 0.42
CHRM2 known ✓ P08172 1/20 0.42
CHRM4 known ✓ P08173 1/20 0.42
HTR1A known ✓ P08908 1/20 0.42
ALDH1A1 P00352 6/20 0.93
LMNA P02545 1/20 0.93
HSD17B10 Q99714 1/20 0.93
TSHR P16473 2/20 0.55
GAA P10253 2/20 0.50
ALOX15 P16050 1/20 0.50
MGAM O43451 1/20 0.50
SI P14410 1/20 0.50
MGAM2 Q2M2H8 1/20 0.50
SOAT1 P35610 1/20 0.50
TRPA1 O75762 1/20 0.46
GLO1 Q04760 1/20 0.44
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Acetate SCHEMBL18498857 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL16267234 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL192603 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL508898 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL525361 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL5036694 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL9731700 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL18237169 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL1163855 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL1150646 1.00 ALDH1A1 (0.93) ALDH1A1LMNAHSD17B10TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240217962-A1 TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE ARVINAS OPERATIONS, INC. 2024-07-04 US disclosed
EP-4358963-A1 SOS1 INHIBITORS Mirati Therapeutics, Inc. (US) 2024-05-01 EP disclosed
CN-117917398-A Ionizable lipid compound, nucleic acid drug molecule delivery system and application 华中师范大学 2024-04-23 CN disclosed
US-11912699-B2 Tau-protein targeting compounds and associated ARVINAS OPERATIONS, INC. (US) 2024-02-27 US disclosed
WO-2023250165-A1 SALTS OF SOS1 INHIBITORS Mirati Therapeutics, Inc. (US) 2023-12-28 WO disclosed
WO-2023231948-A1 ISR INHIBITORS, METHOD FOR PREPARING SAME, AND USE THEREOF 中国药科大学 2023-12-07 WO disclosed
CN-116768877-A ISR inhibitor and preparation method and application thereof 中国药科大学 2023-09-19 CN disclosed
US-11702418-B2 SOS1 inhibitors Mirati Therapeutics, Inc. (US) 2023-07-18 US disclosed
CN-116283707-A Synthesis method of indole compound promoted by visible light 南通大学 2023-06-23 CN disclosed
WO-2023113534-A1 METHOD FOR PREPARATION OF (2R, 3S)-2-(BENZO[D]IMIDAZOLYLPROPYL)PIPERIDIN-3-OL DERIVATIVES 주식회사 대웅제약 2023-06-22 WO disclosed
WO-2021127429-A1 SOS1 INHIBITORS Mirati Therapeutics, Inc. (US) 2021-06-24 WO disclosed
US-20210188857-A1 SOS1 INHIBITORS Mirati Therapeutics, Inc. 2021-06-24 US disclosed
CN-108358838-A Biologically active novel quinoline substitution Shiff base derivative and its synthetic method and application 河南师范大学 2018-08-03 CN disclosed
EP-2660241-A2 C-17-HETEROARYL STEROIDAL COMPOUNDS AS INHIBITORS OF CYP11B, CYP17, AND/OR CYP21 BioMarin Pharmaceutical Inc. (US) 2013-11-06 EP disclosed
EP-2651916-A2 C-17-HETEROARYL STEROIDAL COMPOUNDS AS INHIBITORS OF CYP11B, CYP17, AND/OR CYP21 BioMarin Pharmaceutical Inc. (US) 2013-10-23 EP disclosed
US-20130252930-A1 CYP11B, CYP17, AND/OR CYP21 INHIBITORS BIOMARIN PHARMACEUTICAL INC. (CA) 2013-09-26 US disclosed
CN-103282358-A Cyp11b, cyp17, and/or cyp21 inhibitors BIOMARIN PHARM INC 2013-09-04 CN disclosed
CN-101555259-B Phosphine oxazoline ligand of spiral ring skeleton, a synthetic method thereof and applications in asymmetric hydrogenation of various types of imine coumpounds and various types of non-functionalized SHANGHAI INST ORGANIC CHEM 2012-06-27 CN disclosed
WO-2012083112-A2 CYP11B, CYP17, AND/OR CYP21 INHIBITORS BIOMARIN PHARMACEUTICAL INC. (US) 2012-06-21 WO disclosed
CN-101555259-A Phosphine oxazoline ligand of spiral ring skeleton, a synthetic method thereof and applications in asymmetric hydrogenation of various types of imine coumpounds and various types of non-functionalized SHANGHAI INST ORGANIC CHEM (CN) 2009-10-14 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912699-B2 Tau-protein targeting compounds and associated MAPT, VHL, CRBN CHRM5 4367/4885CHRM1 4354/4885CHRM3 4539/4885
US-20240217962-A1 TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE VHL, CRBN, MAPT CHRM5 4376/4885CHRM1 4407/4885CHRM3 4580/4885
US-20210188857-A1 SOS1 INHIBITORS SOS1, SOS2, SOST CHRM5 4786/4885CHRM1 4763/4885CHRM3 4775/4885
US-11702418-B2 SOS1 inhibitors SOS1, SOS2, SOST CHRM5 4786/4885CHRM1 4763/4885CHRM3 4775/4885
US-20130252930-A1 CYP11B, CYP17, AND/OR CYP21 INHIBITORS CYP4A11, HSD17B11, CYP21A2 CHRM5 4003/4885CHRM1 3224/4885CHRM3 3633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.