SCHEMBL9938973

SCHEMBL9938973

Nc1cc(Cl)ccc1-c1cc(N)c(Cl)c(OC(=O)O)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.40
ABL1 P00519 1/20 0.36
HSP90AA1 P07900 3/20 0.35
HSP90AB1 P08238 3/20 0.35
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
ALOX15 P16050 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MAPK1 P28482 2/20 0.33
DHODH Q02127 1/20 0.33
KMO O15229 1/20 0.33
ALOX12 P18054 1/20 0.33
GCK P35557 1/20 0.33
MARS1 P56192 1/20 0.33
ALPL P05186 1/20 0.33
PTGES O14684 1/20 0.33
ALOX5 P09917 1/20 0.33
CYP2C9 P11712 1/20 0.33
CASP7 P55210 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2468346 0.91 HSP90AA1 (0.47) HSP90AA1HSP90AB1SMN1; SMN2DHODHMARS1
SCHEMBL2470388 0.88 GRM2 (0.41) CYP3A4ABL1HSP90AA1HSP90AB1SMN1; SMN2
SCHEMBL2468072 0.88 KMO (0.47) CYP3A4MAPK1DHODHKMOPTGES
SCHEMBL2468292 0.88 AGPAT2 (0.41) CYP3A4HSP90AA1HSP90AB1ALDH1A1RECQL
SCHEMBL2469714 0.86 HSP90AA1 (0.52) HSP90AA1HSP90AB1ALDH1A1HPGDMAPK1
SCHEMBL2469724 0.85 ACHE (0.40) ALDH1A1HSD17B10
SCHEMBL2468160 0.85 CTRC (0.46) ALDH1A1HPGDHSD17B10KMOALPL
SCHEMBL2469711 0.83 CYP3A4 (0.34) CYP3A4KMO
SCHEMBL2465856 0.82 PPARA (0.36) CYP3A4HSP90AA1HSP90AB1ALDH1A1MAPK1
SCHEMBL2464096 0.81 HSP90AA1 (0.46) ABL1HSP90AA1HSP90AB1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2665710-A1 6-(2-AMINOPHENYL)PICOLINATES AND THEIR USE AS HERBICIDES Bayer Intellectual Property GmbH (DE) 2013-11-27 EP disclosed
WO-2012080187-A1 6-(2-AMINOPHENYL)PICOLINATES AND THEIR USE AS HERBICIDES BAYER CROPSCIENCE AG (DE) 2012-06-21 WO disclosed