Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL659147 | 0.87 | ERN1 (0.34) | MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL6934720 | 0.78 | AOC3 (0.37) | MEN1ALDH1A1KMT2ATDP1L3MBTL1 | |
| SCHEMBL3689758 | 0.77 | LMNA (0.48) | MEN1ALDH1A1KMT2ATDP1L3MBTL1 | |
| SCHEMBL1275599 | 0.77 | GSTP1 (0.34) | MEN1ALDH1A1KMT2AL3MBTL1GSTP1 | |
| SCHEMBL18699457 | 0.75 | HTR1A (0.45) | — | |
| SCHEMBL17205034 | 0.74 | MEN1 (0.31) | MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL4065460 | 0.71 | TRIM24 (0.35) | MEN1ALDH1A1KMT2AL3MBTL1GSTP1 | |
| SCHEMBL10351684 | 0.70 | AOC3 (0.32) | MEN1ALDH1A1KMT2AL3MBTL1GSTP1 | |
| SCHEMBL7189127 | 0.70 | CETP (0.34) | MEN1ALDH1A1KMT2AL3MBTL1GSTP1 | |
| SCHEMBL1275601 | 0.70 | GABRA1 (0.42) | MEN1ALDH1A1KMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655303-B1 | HYDROGENATION OF ESTERS OR CARBONYL GROUPS WITH TETRADENTATE AMINO/IMINO-THIOETHER BASED RUTHENIUM COMPLEXES | FIRMENICH & CIE (CH) | 2017-02-22 | — | — | EP | disclosed |
| US-8614345-B2 | Hydrogenation of esters or carbonyl groups with tetradentate amino/imino-thioether based ruthenium complexes | FIRMENICH SA (CH) | 2013-12-24 | — | — | US | disclosed |
| EP-2655303-A1 | HYDROGENATION OF ESTERS OR CARBONYL GROUPS WITH TETRADENTATE AMINO/IMINO-THIOETHER BASED RUTHENIUM COMPLEXES | Firmenich SA (CH) | 2013-10-30 | — | — | EP | disclosed |
| US-20130274487-A1 | HYDROGENATION OF ESTERS OR CARBONYL GROUPS WITH TETRADENTATE AMINO/IMINO-THIOETHER BASED RUTHENIUM COMPLEXES | FIRMENICH SA (CH) | 2013-10-17 | — | — | US | disclosed |
| WO-2012084810-A1 | HYDROGENATION OF ESTERS OR CARBONYL GROUPS WITH TETRADENTATE AMINO/IMINO-THIOETHER BASED RUTHENIUM COMPLEXES | FIRMENICH SA (CH) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274487-A1 | HYDROGENATION OF ESTERS OR CARBONYL GROUPS WITH TETRADENTATE AMINO/IMINO-THIOETHER BASED RUTHENIUM COMPLEXES | ADH5, ADH1A, ADH1C | MEN1 3804/4885ALDH1A1 45/4885KMT2A 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.