Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953098 | 0.70 | LMNA (0.31) | ALDH1A1KDM4EGAANCOA1NCOA3 | |
| SCHEMBL9952080 | 0.70 | NCOA1 (0.35) | ALDH1A1KDM4EGAANCOA1NCOA3 | |
| SCHEMBL9952278 | 0.67 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAANCOA1NCOA3 | |
| SCHEMBL9928867 | 0.66 | L3MBTL1 (0.45) | ALDH1A1KDM4EGAAIMPDH2 | |
| SCHEMBL9952276 | 0.65 | ALDH1A1 (0.33) | ALDH1A1KDM4EGAANCOA1NCOA3 | |
| SCHEMBL9952084 | 0.65 | LMNA (0.38) | ALDH1A1KDM4EGAANCOA1NCOA3 | |
| SCHEMBL9929296 | 0.64 | HSD17B10 (0.40) | ALDH1A1KDM4EGAAIMPDH2SMN1; SMN2 | |
| SCHEMBL9953040 | 0.64 | IMPDH2 (0.45) | ALDH1A1KDM4EGAAIMPDH2 | |
| SCHEMBL9953105 | 0.64 | AAK1 (0.38) | ALDH1A1KDM4EGAA | |
| SCHEMBL9952029 | 0.63 | TAAR1 (0.46) | IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655374-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | Incyte Corporation (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087881-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |