Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | HCAR1 | Q9BXC0 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954830 | 0.92 | HCAR1 (0.43) | PDE4DHCAR1CA12CA1CA2 | |
| SCHEMBL9954001 | 0.86 | PDE4D (0.56) | PDE4DHCAR1CA12CA1CA2 | |
| SCHEMBL9954005 | 0.84 | HCAR1 (0.40) | PDE4DHCAR1CA12CA1CA2 | |
| SCHEMBL9954505 | 0.84 | PDE7A (0.45) | PDE4DHCAR1PI4KA | |
| SCHEMBL9953324 | 0.81 | HCAR1 (0.50) | HCAR1CA12CA1CA2CA9 | |
| SCHEMBL9953800 | 0.80 | POLB (0.41) | PDE4DHCAR1CA12CA1CA2 | |
| SCHEMBL9954358 | 0.80 | ALDH1A1 (0.53) | PDE4DHCAR1CA12CA1CA2 | |
| SCHEMBL9954224 | 0.79 | CDK9 (0.38) | PDE4DHCAR1CA12CA1CA2 | |
| SCHEMBL9953432 | 0.78 | HCAR1 (0.55) | PDE4DHCAR1KDM4EALDH1A1LMNA | |
| SCHEMBL9953795 | 0.78 | SMN1; SMN2 (0.55) | KDM4EALDH1A1LMNAPI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |